dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0000637
Uniprot Accession O14335; SCR1_SCHPO;
Genbank Protein ID NP_595717.1;
Genbank Nucleotide ID NM_001021615.2;
Protein Name DNA-binding protein scr1
Protein Synonyms/Alias
Gene Name scr1
Gene Synonyms/Alias SPBC1D7.02c;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)
Involved in carbon catabolite repression. Represses the transcription of various genes including the inv1 gene.
Phosphorylation Sites
dbPAF PTMs: 4
PositionPeptidesSourceReferences ( PMIDs )
265MPLSNAPSPPKQMNVcurated22817900
410TFSTRSFSPTPDVTPcurated22817900
424PLVTPAHSPRLRPMDcurated22817900
526SSSRVSVSNLLAGSPcurated22817900
Sequence
(Fasta)
MSEATTATTT GKPSRSTKNP DAPRPYKCPL CTKAFYRLEH QTRHIRTHTG EKPHVCTFPG 60
CAKRFSRSDE LTRHARIHTN ANSRRNAAAA AAANNSARSS NSPAGNLEPS TNNAGVHMTN 120
ASMNPNVNPS YPVFIPQVGM SVAPPVATAA VSMSYPHHYS ASVQQQQATF VSNGQPHNLP 180
AQAQPATIYG IPDALHTTQN GTTIHVTGTP PGAVSQRSEP DSRLSSMNEM QLLASAAANQ 240
LDAAPRITPT KSSGVNLMPL SNAPSPPKQM NVVGSLPSSS NTSPNHLASV PNRGLTSNSS 300
TGSFTKYTNG SSNSLYSNSS MQTPYLPSKS NSSTSLHSMY GVGTTAYAPQ SLRYAHYNYL 360
PYSRPSVSNG FDDDSSSSDF AHFRYQRRSR PVSPCSTAPS SPTFSTRSFS PTPDVTPLVT 420
PAHSPRLRPM DDPSCVQLPS IRSLSLRPSQ VPLIPPLKCD PNAFSASTPA SGAVSRTPSS 480
VSLSSLSNVN SSMPHKPASQ SNVGPVRISS NRRSRKFSSS SRVSVSNLLA GSPPSPSSST 540
KSASSSYSTT TPAFSIGPLT PMTKP 566
Keyword

KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR007087--Znf_C2H2
IPR015880--Znf_C2H2-like
IPR013087--Znf_C2H2/integrase_DNA-bd

PROSITE

PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2

Pfam
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0046872--F:metal ion binding
GO:0000978--F:RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000982--F:transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0006351--P:transcription, DNA-templated