dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0000627
Uniprot Accession O14295; PLR1_SCHPO; O94234; P78855;
Genbank Protein ID NP_594584.1;
Genbank Nucleotide ID NM_001020013.2;
Protein Name Pyridoxal reductase
Protein Synonyms/Alias
Gene Name plr1
Gene Synonyms/Alias plr;SPAC9E9.11;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)
Catalyzes the reduction of pyridoxal (PL) with NADPH and oxidation of pyridoxine (PN) with NADP(+).
Phosphorylation Sites
dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
292TSVSRTKSNLNALNKdbPTM 3.0;SysPTM 2.0;UniProt;curated18257517; 16381945; 23193290; 19366988; 22817900
300NLNALNKSLSPEQFKcurated22817900
Sequence
(Fasta)
MPIVSGFKVG PIGFGLMGLT WKPKQTPDEE AFEVMNYALS QGSNYWDAGE FYGVDPPTSN 60
LDLLARYFEK YPENANKVFL SVKGGLDFKT LVPDGNPDFV SKSVENVIAH LRGTKKLDLF 120
QCARVDPNVP IETTMKTLKG FVDSGKISCV GLSEVSAETI KRAHAVVPIA AVEVEYSLFS 180
RDIETNGIMD ICRKLSIPII AYSPFCRGLL TGRIKTVEDL KEFAKSFPFL EYLDRFSPDV 240
FAKNLPFLQA VEQLAKKFGM TMPEFSLLFI MASGNGLVIP IPGSTSVSRT KSNLNALNKS 300
LSPEQFKEAK EVLSKYPIYG LRYNEQLAGT LSV 334
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0903--Direct protein sequencing
KW-0521--NADP
KW-0560--Oxidoreductase
KW-0597--Phosphoprotein
KW-1185--Reference proteome

Interpro

IPR001395--Aldo/ket_red/Kv-b
IPR023210--NADP_OxRdtase_dom

PROSITE
Pfam

PF00248--Aldo_ket_red

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0004033--F:aldo-keto reductase (NADP) activity
GO:0016491--F:oxidoreductase activity
GO:0050236--F:pyridoxine:NADP 4-dehydrogenase activity
GO:0042821--P:pyridoxal biosynthetic process
GO:0042820--P:vitamin B6 catabolic process