dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0000615
Uniprot Accession O14253; NCBP1_SCHPO;
Genbank Protein ID NP_594104.1;
Genbank Nucleotide ID NM_001019528.2;
Protein Name Nuclear cap-binding protein subunit 1
Protein Synonyms/Alias 80 kDa nuclear cap-binding protein;CBP80;NCBP 80 kDa subunit;
Gene Name cbc1
Gene Synonyms/Alias SPAC6G10.07;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)
Component of the CBC complex, which binds cotranscriptionally to the 5'-cap of pre-mRNAs and is involved in maturation, export and degradation of nuclear mRNAs.
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
29FRPHRGNSQELLAARdbPTM 3.0;UniProt;curated18257517; 16381945; 23193290; 22817900
Sequence
(Fasta)
MSSYRGSTRP RKRTREGENY GFRPHRGNSQ ELLAARIKKD ITFLADPRGN SVAADDINYV 60
AMSLSREAND PETISTILDC IQTTAFIIPV KIPHLATLII RASLRVPLIL EKAAAYFCLQ 120
YFTNLNSFLY YEAKVDLRML ICMSFALQPG TLKPLFSLLA DAISKETKPS VWGDNFLRII 180
LINLPYFIAA NNDLGKKDFA NEILDQCEIY VRHRKSSITL SNPLSIHDNL SEEELDLLYK 240
QLILSRENDF TFPYISQPWK FFESDFVHIV PVSPSIPEWT FQPTPQQNEL PSFKRFFELF 300
NNFEIRTTPD ASDVAASIFR DISVDVINHL EFNRVEAAQV LTDLDVYFTY KTFALRGTPV 360
NELPNLDPSE SRWKAEDIIV EAVLGELLGS QNTTYKPVYY HSLLIECCRI APKILAPTFG 420
RVIRLMYTMS SDLPLQTLDR FIDWFSHHLS NFNFHWKWNE WIPDVELDDL HPKKVFMRET 480
ITRELILSYY TRISDSLPEE LRCLLGEQPS GPNFVYENET HPLYQQSSQI IEALRLHKPL 540
EELDIILQSE EIQNSETSAV RLVMSCAYSL GSRSFSHALN VFEKHLNTLK HFSRKSLDSE 600
IEVVDELFSF WKLQPFNAVM WLDKMLNYSI ISITSIIEWL IKQDVTIWSR SYTWSLVNTT 660
FNKLAARLRR SVSNKEDSSL INEANEEKEI VTNLLLSALR ALISENAENI WVSHWLNLML 720
KYVESNFLSV KKDTIEEANE PVQENTSEEQ EDTKMQPVDA VDEQPSENNQ TAADATNEEK 780
781
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0507--mRNA processing
KW-0508--mRNA splicing
KW-0509--mRNA transport
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0694--RNA-binding
KW-0813--Transport

Interpro

IPR016024--ARM-type_fold
IPR027159--CBP80
IPR016021--MIF4-like
IPR015172--MIF4G-like_typ-1
IPR015174--MIF4G-like_typ-2
IPR003890--MIF4G-like_typ-3

PROSITE
Pfam

PF02854--MIF4G
PF09088--MIF4G_like
PF09090--MIF4G_like_2

Gene Ontology

GO:0005829--C:cytosol
GO:0072686--C:mitotic spindle
GO:0005846--C:nuclear cap binding complex
GO:0005634--C:nucleus
GO:0048471--C:perinuclear region of cytoplasm
GO:0003729--F:mRNA binding
GO:0000339--F:RNA cap binding
GO:0045292--P:mRNA cis splicing, via spliceosome
GO:0051028--P:mRNA transport
GO:0000184--P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay