dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000612
Uniprot Accession O14248; TEA3_SCHPO;
Genbank Protein ID NP_594099.1;
Genbank Nucleotide ID NM_001019523.2;
Protein Name Tip elongation aberrant protein 3
Protein Synonyms/Alias Cell polarity protein tea3;
Gene Name tea3
Gene Synonyms/Alias SPAC6G10.02c;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)		 Acts as a cell end marker required for efficient new end take-off (NETO), whereby growth is activated at the cell end to generate bipolarity in extending cells. Also required for proper placement of the septum.
Phosphorylation Sites
 dbPAF PTMs: 15
PositionPeptidesSourceReferences ( PMIDs )
179HSMLLVDSKLWIFGGcurated22817900
430PNHSKKNSVTSTSSSdbPTM 3.0;UniProt18257517; 16381945; 23193290
437SVTSTSSSQFNNFLEdbPTM 3.0;UniProt18257517; 16381945; 23193290
460ARHRHYASLDEQGLHdbPTM 3.0;SysPTM 2.0;UniProt;curated18257517; 16381945; 23193290; 19366988; 22817900
523SRSSESSSPINESESdbPTM 3.0;UniProt;curated18257517; 16381945; 23193290; 22817900
688QLLKQNESASELLKScurated22817900
950KITQRKLSEVQIALAdbPTM 3.0;SysPTM 2.0;curated18257517; 16381945; 23193290; 19366988; 22817900
980VHLPTDFSASSSPLRdbPTM 3.0;UniProt;curated18257517; 16381945; 23193290; 22817900
982LPTDFSASSSPLRSYdbPTM 3.0;UniProt18257517; 16381945; 23193290
983PTDFSASSSPLRSYFdbPTM 3.0;UniProt18257517; 16381945; 23193290
984TDFSASSSPLRSYFNdbPTM 3.0;SysPTM 2.0;UniProt;curated18257517; 16381945; 23193290; 19366988; 22817900
1045NDLHKRLSDVINSQQdbPTM 3.0;SysPTM 2.0;curated18257517; 16381945; 23193290; 19366988; 22817900
1058QQKFLSLSPQVSKDYdbPTM 3.0;SysPTM 2.0;curated18257517; 16381945; 23193290; 19366988; 22817900
1078KLNDTAGSFSGEEMRdbPTM 3.0;SysPTM 2.0;UniProt;curated18257517; 16381945; 23193290; 19366988; 22817900
1080NDTAGSFSGEEMRAIdbPTM 3.0;SysPTM 2.0;UniProt;curated18257517; 16381945; 23193290; 19366988; 22817900
Sequence
(Fasta)		MVQKVLSRQS DNSQDVSAEQ LDVVESGSID QQNIRAWVVR KVKENDKRTS TNQSFKWEAV 60
KPASCLDAAN EKFMYLHGGR EKSGISNSLF KLDLDSCTVY SHNRGEDNDS PARVGHSIVC 120
SADTIYLFGG CDSETDSTFE VGDNSLYAYN FKSNQWNLVS TQSPLPSPRT GHSMLLVDSK 180
LWIFGGECQG KYLNDIHLFD TKGVDRRTQS ELKQKANANN VEKANMEFDE TDWSWETPFL 240
HSSSPPPRSN HSVTLVQGKI FVHGGHNDTG PLSDLWLFDL ETLSWTEVRS IGRFPGPREG 300
HQATTIDDTV YIYGGRDNKG LILNELWAFN YSQQRWSLVS NPIPILLSDS SSYKIVSKNN 360
HILLLYLNAL DAPKQLLCYE ADPKNLYWDK DKFSDIPVLQ HISMKPSNAS NHTVSLGYLN 420
DRPNHSKKNS VTSTSSSQFN NFLEQNQKAV RSARHRHYAS LDEQGLHSLR NLSKTSGMNH 480
SADFSLHEFG QADPFAYEIE KPIASLPLPN GNDTISRSSE SSSPINESES NSLLKLQSDF 540
KFSNSDDRVA WLEEQLLYCM QQGYTLKPPN LFQHVDEKLR LEKKEQLSYL EILKVIEQML 600
ESNEQKFKKQ IVSLASENAK LAAQRDAAVE NANYSRSLIQ KKTTDETVGS LIEKVGKLEY 660
EVQGTLEEAT SYYQKNTELQ QLLKQNESAS ELLKSRNEKL CVDYDKLRSV FEEDSSKILS 720
LQKENENLQS QILQISEELV DYRSRCEALE YGNYELETKL IEMHDRVEMQ TNVIEASASA 780
LDVSNTAILS FEDSLRRERD EKSTLQQKCL NLQYEYENVR IELENLQSRA LELESALEQS 840
VSDAKYSKAI MQSGLSKLLS SINENKDNLK EFSKSKQKIS YLESQLEGLH ELLRESQRLC 900
EGRTKELLNS QQKLYDLKHS YSSVMTEKSK LSDQVNDLTE QAKITQRKLS EVQIALADSK 960
MNQQLSGKDS TDVHLPTDFS ASSSPLRSYF NEEDSFNNAS AAHSSKESDI PSGGVFTKYR 1020
NHFGNLMTSE ETKAPDNNDL HKRLSDVINS QQKFLSLSPQ VSKDYYDVRS KLNDTAGSFS 1080
GEEMRAIDDN YYASRIKQLE DDYQKAITYA NCSDESFQQL SHSFM 1126
Keyword

KW-0131--Cell cycle
KW-0132--Cell division
KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0717--Septation
Interpro

IPR011043--Gal_Oxase/kelch_b-propeller
IPR015915--Kelch-typ_b-propeller
PROSITE
Pfam
Gene Ontology

GO:0051285--C:cell cortex of cell tip
GO:0032153--C:cell division site
GO:0030428--C:cell septum
GO:0005737--C:cytoplasm
GO:0000917--P:barrier septum assembly
GO:1902405--P:mitotic actomyosin contractile ring localization
GO:0061160--P:regulation of establishment of bipolar cell polarity regulating cell shape