dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0000611
Uniprot Accession O14243; SNX4_SCHPO; P78806;
Genbank Protein ID NP_593905.1;
Genbank Nucleotide ID NM_001019335.2;
Protein Name Sorting nexin-4
Protein Synonyms/Alias Autophagy-related protein 24;
Gene Name snx4
Gene Synonyms/Alias atg24;SPAC6F6.12;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)
Sorting nexin, involved in the separation or division of vacuoles throughout the entire life cycle of the cells. Involved in retrieval of late-Golgi SNAREs from post-Golgi endosomes to the trans-Golgi network, for cytoplasm to vacuole transport (Cvt), mitophagy, and pexophagy (By similarity).
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
62CKVRRRFSDFVKLQEdbPTM 3.0;UniProt;curated18257517; 16381945; 23193290; 22817900
Sequence
(Fasta)
MSDSVNLDEP STNSTHFLQC LVTEPRKELQ GSRDTHVSYL IITKTNLSIF TRAECKVRRR 60
FSDFVKLQEI LSRMNEDCVV PPLPAKHKLE YIKGGRFSDN FINRRAKLLN RYITRCALHP 120
VLHQSPHFIA FLENPNWNNY VRFFIQPKLN NTSKLDEISD SLLNAFSKLK EEPTEFDIQR 180
DHVQQFMFGI SNLEGSIQKL LRLEKALESD YEDVSIQFDR LASLDQALDV PIESIQNALQ 240
QTGTEYANLT EKLTLLLDTI KDVESYAHSL KELLKRRDQK QQDVEALQEY SAKLSLERDK 300
ISSGGSNGFS LSKTLDDLRG IDHNDTRLKR LEHVQSELQA VEQAIQEASA VHDAFNQRVR 360
EESKLFDSVR QSEMLSAISD YANVHVEFFT NIRDLWIRVK Q 402
Keyword

KW-0072--Autophagy
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0967--Endosome
KW-0446--Lipid-binding
KW-0472--Membrane
KW-0597--Phosphoprotein
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport

Interpro

IPR001683--Phox

PROSITE

PS50195--PX

Pfam

PF00787--PX

Gene Ontology

GO:0005776--C:autophagosome
GO:0005737--C:cytoplasm
GO:0005768--C:endosome
GO:0010008--C:endosome membrane
GO:0019898--C:extrinsic component of membrane
GO:0005794--C:Golgi apparatus
GO:0000407--C:pre-autophagosomal structure
GO:0035091--F:phosphatidylinositol binding
GO:0032266--F:phosphatidylinositol-3-phosphate binding
GO:0006914--P:autophagy
GO:0032258--P:CVT pathway
GO:0034498--P:early endosome to Golgi transport
GO:0006897--P:endocytosis
GO:0034727--P:piecemeal microautophagy of nucleus
GO:0006623--P:protein targeting to vacuole
GO:0016050--P:vesicle organization