dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000609
Uniprot Accession O14236; NOG2_SCHPO; Q9US70;
Genbank Protein ID NP_593896.1;
Genbank Nucleotide ID NM_001019326.2;
Protein Name Nucleolar GTP-binding protein 2
Protein Synonyms/Alias
Gene Name nog2
Gene Synonyms/Alias SPAC6F6.03c;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)		 GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation.
Phosphorylation Sites
 dbPAF PTMs: 4
PositionPeptidesSourceReferences ( PMIDs )
153QRKRPKISFDSVAELcurated22817900
186ILANPDESDDVMLAAdbPTM 3.0;UniProt;curated18257517; 16381945; 23193290; 22817900
484QKVATQQTEGSDQDGdbPTM 3.0;UniProt18257517; 16381945; 23193290
487ATQQTEGSDQDGEEAdbPTM 3.0;UniProt;curated18257517; 16381945; 23193290; 22817900
Sequence
(Fasta)		MGTYKKEKSR IGREGANEKK PGNLRVKGEN FYRNAKDVAR VNMYRGGKAK YNAAGELVRA 60
AEFQSSEVPK ARIQPDRRWF NNTRVIAQPT LTQFREAMGQ KLNDPYQVLL RRNKLPMSLL 120
QENTEIPKVR VLESEPFENT FGPKSQRKRP KISFDSVAEL AKESDEKQNA YEEKIEERIL 180
ANPDESDDVM LAARDAIFSK GQSKRIWNEL YKVIDSSDVL IQVLDARDPV GTRCGTVERY 240
LRNEASHKHM ILVLNKVDLV PTSVAAAWVK ILAKEYPTIA FHASINNSFG KGSLIQILRQ 300
FASLHSDKKQ ISVGLIGFPN AGKSSIINTL RKKKVCNVAP IPGETKVWQY VALMKRIFLI 360
DCPGIVPPSS NDSDAELLLK GVVRVENVSN PEAYIPTVLS RCKVKHLERT YEISGWNDST 420
EFLAKLAKKG GRLLKGGEPD EASVAKMVLN DFMRGKIPWF IGPKGLSSSN DEINSSQKVA 480
TQQTEGSDQD GEEAEEEWHG ISDDGKADES ESTKPVAEGS ASESTDESAV DDNKNRS 538
Keyword

KW-0181--Complete proteome
KW-0342--GTP-binding
KW-0547--Nucleotide-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0690--Ribosome biogenesis
Interpro

IPR030378--G_CP_dom
IPR023179--GTP-bd_ortho_bundle
IPR006073--GTP_binding_domain
IPR024929--NOG2
IPR012971--NOG2_N_dom
IPR027417--P-loop_NTPase
PROSITE

PS51721--G_CP
Pfam

PF01926--MMR_HSR1
PF08153--NGP1NT
Gene Ontology

GO:0072686--C:mitotic spindle
GO:0044732--C:mitotic spindle pole body
GO:0005730--C:nucleolus
GO:0005634--C:nucleus
GO:0005525--F:GTP binding
GO:0003924--F:GTPase activity
GO:0000055--P:ribosomal large subunit export from nucleus
GO:0042254--P:ribosome biogenesis