dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000607
Uniprot Accession O14224; GDIR_SCHPO;
Genbank Protein ID NP_593292.1;
Genbank Nucleotide ID NM_001018722.2;
Protein Name Rho GDP-dissociation inhibitor
Protein Synonyms/Alias
Gene Name SPAC6F12.06
Gene Synonyms/Alias
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)		 Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them.
Phosphorylation Sites
 dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
63GITGTGYSPSNDRRTdbPTM 3.0;UniProt18257517; 16381945; 23193290
Sequence
(Fasta)		MSVNNEVSAD QHNPELEDDT FEHGPPVSLG EKKSLNEYMK MDAEDESLQK WKASLGITGT 60
GYSPSNDRRT VVILKLSLLV DGRDPVDVNM EDAASVEQIR KKGFTIKEGS EFKIGVKFRV 120
QHEVISGLRY VQTVRRRGFV VDKTSTMIGS YGPSETPYDF TSEPDEAPTG MLARGHYEAN 180
GKFVDDDKVV HHEFVWAFDV AKSWK 206
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
Interpro

IPR014756--Ig_E-set
IPR000406--Rho_GDI
IPR024792--RhoGDI_domain
PROSITE
Pfam

PF02115--Rho_GDI
Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0005094--F:Rho GDP-dissociation inhibitor activity
GO:0007015--P:actin filament organization
GO:0050790--P:regulation of catalytic activity
GO:0007264--P:small GTPase mediated signal transduction