dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000605
Uniprot Accession O14216; SLD2_SCHPO;
Genbank Protein ID NP_593766.1;
Genbank Nucleotide ID NM_001019196.2;
Protein Name DNA replication regulator sld2
Protein Synonyms/Alias DNA replication and checkpoint protein 1;
Gene Name drc1
Gene Synonyms/Alias sld2;SPAC6B12.11;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)		 Has a role in the initiation of DNA replication. Required at S-phase checkpoint.
Phosphorylation Sites
 dbPAF PTMs: 6
PositionPeptidesSourceReferences ( PMIDs )
60LKRESSITPKKAKTKdbPTM 3.011937031; 16381945; 23193290
74KVDFKFQTPTKQRAEdbPTM 3.011937031; 16381945; 23193290
87AETEANESPKAPRNDdbPTM 3.011937031; 16381945; 23193290
99RNDYLQVTPKTVDKSdbPTM 3.0;SysPTM 2.0;curated11937031; 16381945; 23193290; 18257517; 19366988; 22817900
154SSTMIPTTPSKNPEPdbPTM 3.011937031; 16381945; 23193290
183YRLQVYTSPNLLRVNdbPTM 3.0;UniProt18257517; 16381945; 23193290
Sequence
(Fasta)		MHDESRTKQI SSIKALLKKW EHEYVHTNNC KPSKEDVKKQ PEIALLYKQY YELKRESSIT 60
PKKAKTKVDF KFQTPTKQRA ETEANESPKA PRNDYLQVTP KTVDKSLLGP TPQLSRRVLN 120
LLEDMSPIAD SHVDQISDIK HNTSEISSTM IPTTPSKNPE PVAQHTPTVL ETPSSYRLQV 180
YTSPNLLRVN APCRKSLSEM LRELKDIEDD YGSNEEKILQ EFESFSSSSS ESLVDRDISQ 240
PMKKKIKRQN RLVKLPPSMN LSKSHLEGLP EIDEDAENGI DDNEDTTASK DSSPFLDLQS 300
ERQNKKIMRN GLVIGKQVSQ NYSSYKLKKR KFRRHRS 338
Keyword

KW-0131--Cell cycle
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0235--DNA replication
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
Interpro

IPR021110--DNA_rep_checkpnt_protein
PROSITE
Pfam

PF11719--Drc1-Sld2
Gene Ontology

GO:0005829--C:cytosol
GO:0043596--C:nuclear replication fork
GO:0005634--C:nucleus
GO:1902969--P:mitotic DNA replication
GO:1902977--P:mitotic DNA replication preinitiation complex assembly