dbPAF Protein Information
| Tag | Content | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| dbPAF ID | dbPAF-0000600 | ||||||||
| Uniprot Accession | O14205; VPS74_SCHPO; Q9P7C4; | ||||||||
| Genbank Protein ID | XP_001713053.1; | ||||||||
| Genbank Nucleotide ID | XM_001713001.2; | ||||||||
| Protein Name | Vacuolar protein sorting-associated protein 74 | ||||||||
| Protein Synonyms/Alias | |||||||||
| Gene Name | vps74 | ||||||||
| Gene Synonyms/Alias | SPAC5D6.13;SPAPJ735.02c; | ||||||||
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast) | ||||||||
| NCBI Taxa ID | 284812 | ||||||||
| Functional Description (View all) |
Phosphatidylinositol-4-phosphate-binding protein that links Golgi membranes to the cytoskeleton and may participate in the tensile force required for vesicle budding from the Golgi. Thereby, may play a role in Golgi membrane trafficking and could indirectly give its flattened shape to the Golgi apparatus. May also bind to the coatomer to regulate Golgi membrane trafficking. May play a role in anterograde transport from the Golgi to the plasma membrane and regulate secretion. Mediates the cis and medial Golgi localization of mannosyltransferases through direct binding of their cytosolic domains. Involved in vacuolar protein sorting (By similarity). | ||||||||
| Phosphorylation Sites |
dbPAF PTMs: 1
|
||||||||
| Sequence (Fasta) | MSGGLSRRRV AAASSDEERP EMRSVSHSKS HLEGYDDDHK IAFDPKDLEQ GAEREKQPRL 60 TLMEEVLLLG LKDKQGYLSF WNDSISYSLR GCILMELAFR GKLRMQKDVN RKRFPLADRV 120 VELVDEKLTG EVLLDEAIKM IHTSELMSVT SWIDLMSGET WNVMKIGYQL RQVRERLAKG 180 LVDKGILRNE KKNFLLFDMP THPIADTSIK DSIKKRVVSV LTSRVIEIDN SPSFPEYLSF 240 RCLRTVALAC SSYAANVLEN ALDNLNYEDR EKAFSRVDEL LCDFSQWPFD LHASSSVGAN 300 LPELISEELS SVKEEQLLFI EVVAAVLQVF THLDSLL 338 |
||||||||
| Keyword | KW-0181--Complete proteome |
||||||||
| Interpro | IPR008628--GPP34 |
||||||||
| PROSITE | |||||||||
| Pfam | PF05719--GPP34 |
||||||||
| Gene Ontology | GO:0005829--C:cytosol |