dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0000598
Uniprot Accession O14200; PXA1_SCHPO; P78842;
Genbank Protein ID NP_593362.1;
Genbank Nucleotide ID NM_001018794.2;
Protein Name PXA domain protein 1
Protein Synonyms/Alias
Gene Name pxa1
Gene Synonyms/Alias SPAC5D6.07c;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)
Required for required for normal vacuolar morphology and for vacuolar protein transport. Also required for endosome-to-Golgi protein transport.
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
420KSHQRSFSIPKATKDcurated22817900
Sequence
(Fasta)
MAKLSSLLNP IISKILEIYV YSWYSGISKD ALFPSQCEQV GGSIVHELEK RLSRQDAMDL 60
LFYEIPFLLI KHIENTEEAK LRFALPQGQI LEIDTIYHSL HPHIALEKEE NELVYCRLLV 120
EDILKYLLPA TNSKSEIECV ILREALAVQI HKSIQVASSP ETMYKFIIYL SKAILQPSRR 180
PWKESITTAV RWVWHAFRIL LITRGVPYFS TAWFQFYLKL FSQKDNVSSS DLTRWFFFYT 240
LLYPWIALVS AFVAETMTLC CIVTIFYDKN VNRQWKQYIL TSVSNMDKGN PSGGSQSTNV 300
TTFRRFSQSS YPRRSNYRRR ISTSSKSLYE LSPSKFKSIP ITSNPPPMLN LSKGSTSVEP 360
TFCETNASVA LSTVTSTPVF STDSSPLSSR TRENLLSLIP SAVSSPTKAN TNKSHQRSFS 420
IPKATKDSQT PSENSAATLK QAAIDAYSQI PVIPFFLPSD KLIMLVESEY RNKHIFYSLL 480
NSFTMVMFPE LRHTK 496
Keyword

KW-0181--Complete proteome
KW-0967--Endosome
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0813--Transport

Interpro

IPR003114--Phox_assoc
IPR013996--PXA_dom

PROSITE

PS51207--PXA

Pfam

PF02194--PXA

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005768--C:endosome
GO:0031303--C:integral component of endosome membrane
GO:0034613--P:cellular protein localization
GO:0032511--P:late endosome to vacuole transport via multivesicular body sorting pathway
GO:0015031--P:protein transport
GO:0042147--P:retrograde transport, endosome to Golgi
GO:0007165--P:signal transduction
GO:0007033--P:vacuole organization