dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000595
Uniprot Accession O14189; PP2C5_SCHPO; O42655;
Genbank Protein ID NP_593268.2;
Genbank Nucleotide ID NM_001018665.2;
Protein Name Protein phosphatase 2C homolog C10F6.17c
Protein Synonyms/Alias Pyruvate dehydrogenase (Lipoamide) phosphatase C10F6.17c;
Gene Name SPAC10F6.17c
Gene Synonyms/Alias
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)		 Involved in regulation of pyruvate dehydrogenase activity.
Phosphorylation Sites
 dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
310HREYFSASPIPVKTPcurated22817900
Sequence
(Fasta)		MNFFTSAVGS KVFKRNNFKY VAIAASSIGL AAYHIRKDAI ALDIPNSTYQ HVSKNRVPPT 60
DGDGITKRLK EFERTVTVNK DGIFRYDFNQ VASNDPCEDD HVEVIDRNID EGNWYFWGIF 120
DGHSGWNTSL FLRQHLVPAV VRELQKCTAS YYHQNACPSS LALDKSISEA FAKVDHQIVH 180
EHVSHVFNNP ESLQVAASLL LPALSGSCAL LTSYSAKSKS LQVACTGDSR AVLGECTPDG 240
SWEAIPLSRD QTGMNPDEAS RLEVEHPGEE VLRNNRILGR LMPSRAFGDA RYKWSQEISE 300
RLHREYFSAS PIPVKTPPYV TAVPEIESIT VNPKKHRFLI MASDGLWDTM SSEQAVQLVG 360
EWADTVLGKT TNEKNTTQDD KQSWSLFKKT SKVIDDNAAT HLIRHSLGGS DQRISALLTL 420
TYPISRRYRD DITVTVIFFD EKTL 445
Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0460--Magnesium
KW-0464--Manganese
KW-0479--Metal-binding
KW-0496--Mitochondrion
KW-0904--Protein phosphatase
KW-1185--Reference proteome
Interpro

IPR015655--PP2C
IPR001932--PPM-type_phosphatase_dom
PROSITE

PS51746--PPM_2
Pfam

PF00481--PP2C
Gene Ontology

GO:0005739--C:mitochondrion
GO:0004741--F:[pyruvate dehydrogenase (lipoamide)] phosphatase activity
GO:0046872--F:metal ion binding
GO:0004722--F:protein serine/threonine phosphatase activity
GO:0006091--P:generation of precursor metabolites and energy