| Tag |
Content |
| dbPAF ID |
dbPAF-0000583 |
| Uniprot Accession |
O14139; HRP3_SCHPO;
|
| Genbank Protein ID |
NP_594967.1;
|
| Genbank Nucleotide ID |
NM_001020398.2;
|
| Protein Name |
Chromodomain helicase hrp3 |
| Protein Synonyms/Alias |
ATP-dependent helicase hrp3; |
| Gene Name |
hrp3 |
| Gene Synonyms/Alias |
SPAC3G6.01; |
| Organism |
Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast) |
| NCBI Taxa ID |
284812 |
Functional Description
(View all) |
Involved in heterochromatin silencing. Required for transcriptional repression at the silence loci of mat3, where it has a direct role as a chromatin remodeling factor.Functional Description
Involved in heterochromatin silencing. Required for transcriptional repression at the silence loci of mat3, where it has a direct role as a chromatin remodeling factor. |
Phosphorylation Sites
|
dbPAF PTMs: 3 |
Sequence
(Fasta) | MSTSAIALAL SSSKAIEQLD HVQTETPNLK QEMSESPSNS GVASKRKLQS TEWLDPELYG 60
LRRSGRTRSN PGRYVDTDDQ EDVFPSKHRK GTRNGSSFSR HRTIRDLDDE AESVTSEESE 120
SDDSSYGGTP KKRSRQKKSN TYVQDEIRFS SRNSKGVNYN EDAYFESFEE EEEEEMYEYA 180
TEVSEEPEDT RAIDVVLDHR LIEGHDGSTP SEDYEFLIKW VNFSHLHCTW EPYNNISMIR 240
GSKKVDNHIK QVILLDREIR EDPTTTREDI EAMDIEKERK RENYEEYKQV DRIVAKHLNS 300
DGSVEYLVKW KQLLYDFCTW EASSIIEPIA ATEIQAFQER EESALSPSRG TNYGNSRPKY 360
RKLEQQPSYI TGGELRDFQL TGVNWMAYLW HKNENGILAD EMGLGKTVQT VAFLSYLAHS 420
LRQHGPFLVV VPLSTVPAWQ ETLALWASDM NCISYLGNTT SRQVIRDYEF YVDGTQKIKF 480
NLLLTTYEYV LKDRSVLSNI KWQYMAIDEA HRLKNSESSL YEALSQFKNS NRLLITGTPL 540
QNNIRELAAL VDFLMPGKFE IREEINLEAP DEEQEAYIRS LQEHLQPYIL RRLKKDVEKS 600
LPSKSERILR VELSDLQMYW YKNILTRNYR VLTQSISSGS QISLLNIVVE LKKASNHPYL 660
FDGVEESWMQ KINSQGRRDE VLKGLIMNSG KMVLLDKLLS RLRRDGHRVL IFSQMVRMLD 720
ILGDYLSLRG YPHQRLDGTV PAAVRRTSID HFNAPNSPDF VFLLSTRAGG LGINLMTADT 780
VIIFDSDWNP QADLQAMARA HRIGQKNHVM VYRLLSKDTI EEDVLERARR KMILEYAIIS 840
LGVTDKQKNS KNDKFSAEEL SAILKFGASN MFKAENNQKK LEDMNLDEIL EHAEDHDTSN 900
DVGGASMGGE EFLKQFEVTD YKADVSWDDI IPLTEREKFE EEDRLREEEE ALKQEIELSS 960
RRGNRPYPSS AVESPSYSGT SERKSKKQML KDEVLLEKEI RLLYRAMIRY GSLEHRYNDI 1020
VKYADLTTQD AHVIKKIAAD LVTASRKAVS AAEKDLSNDQ SNNKSSRKAL LITFKGVKNI 1080
NAETLVQRLN DLDILYDAMP TSGYSNFQIP MHVRSVHGWS CQWGPREDSM LLSGICKHGF 1140
GAWLEIRDDP ELKMKDKIFL EDTKQTDNSV PKDKENKEKK VPSAVHLVRR GEYLLSALRE 1200
HHQNFGIKSS PAISTNGKTQ PKKQTANRRQ SGKPNVKSAQ KIESATRTPS PAISESRKKP 1260
SSKDTKIETP SREQSRSQTA SPVKSEKDDG NVSLNAEQKA RCKELMYPVR KHMKRLRKDS 1320
SGLGRAELVK LLTECLTTIG KHIEKTVNDT PSEEKATVRK NLWMFACYFW PKEEVKYTSL 1380
ISMYEKMK
1389Fasta Sequence
>O14139|hrp3|Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
MSTSAIALALSSSKAIEQLDHVQTETPNLKQEMSESPSNSGVASKRKLQSTEWLDPELYGLRRSGRTRSNPGRYVDTDDQEDVFPSKHRKGTRNGSSFSRHRTIRDLDDEAESVTSEESESDDSSYGGTPKKRSRQKKSNTYVQDEIRFSSRNSKGVNYNEDAYFESFEEEEEEEMYEYATEVSEEPEDTRAIDVVLDHRLIEGHDGSTPSEDYEFLIKWVNFSHLHCTWEPYNNISMIRGSKKVDNHIKQVILLDREIREDPTTTREDIEAMDIEKERKRENYEEYKQVDRIVAKHLNSDGSVEYLVKWKQLLYDFCTWEASSIIEPIAATEIQAFQEREESALSPSRGTNYGNSRPKYRKLEQQPSYITGGELRDFQLTGVNWMAYLWHKNENGILADEMGLGKTVQTVAFLSYLAHSLRQHGPFLVVVPLSTVPAWQETLALWASDMNCISYLGNTTSRQVIRDYEFYVDGTQKIKFNLLLTTYEYVLKDRSVLSNIKWQYMAIDEAHRLKNSESSLYEALSQFKNSNRLLITGTPLQNNIRELAALVDFLMPGKFEIREEINLEAPDEEQEAYIRSLQEHLQPYILRRLKKDVEKSLPSKSERILRVELSDLQMYWYKNILTRNYRVLTQSISSGSQISLLNIVVELKKASNHPYLFDGVEESWMQKINSQGRRDEVLKGLIMNSGKMVLLDKLLSRLRRDGHRVLIFSQMVRMLDILGDYLSLRGYPHQRLDGTVPAAVRRTSIDHFNAPNSPDFVFLLSTRAGGLGINLMTADTVIIFDSDWNPQADLQAMARAHRIGQKNHVMVYRLLSKDTIEEDVLERARRKMILEYAIISLGVTDKQKNSKNDKFSAEELSAILKFGASNMFKAENNQKKLEDMNLDEILEHAEDHDTSNDVGGASMGGEEFLKQFEVTDYKADVSWDDIIPLTEREKFEEEDRLREEEEALKQEIELSSRRGNRPYPSSAVESPSYSGTSERKSKKQMLKDEVLLEKEIRLLYRAMIRYGSLEHRYNDIVKYADLTTQDAHVIKKIAADLVTASRKAVSAAEKDLSNDQSNNKSSRKALLITFKGVKNINAETLVQRLNDLDILYDAMPTSGYSNFQIPMHVRSVHGWSCQWGPREDSMLLSGICKHGFGAWLEIRDDPELKMKDKIFLEDTKQTDNSVPKDKENKEKKVPSAVHLVRRGEYLLSALREHHQNFGIKSSPAISTNGKTQPKKQTANRRQSGKPNVKSAQKIESATRTPSPAISESRKKPSSKDTKIETPSREQSRSQTASPVKSEKDDGNVSLNAEQKARCKELMYPVRKHMKRLRKDSSGLGRAELVKLLTECLTTIGKHIEKTVNDTPSEEKATVRKNLWMFACYFWPKEEVKYTSLISMYEKMK
|
| Keyword |
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0347--Helicase
KW-0378--Hydrolase
KW-0547--Nucleotide-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
|
| Interpro |
IPR000953--Chromo/shadow_dom
IPR023780--Chromo_domain
IPR016197--Chromodomain-like
IPR023779--Chromodomain_CS
IPR025260--DUF4208
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase
IPR000330--SNF2_N
|
| PROSITE |
PS00598--CHROMO_1
PS50013--CHROMO_2
PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
|
| Pfam |
PF00385--Chromo
PF13907--DUF4208
PF00271--Helicase_C
PF00176--SNF2_N
|
| Gene Ontology |
GO:0031934--C:mating-type region heterochromatin
GO:0000790--C:nuclear chromatin
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0004003--F:ATP-dependent DNA helicase activity
GO:0003677--F:DNA binding
GO:0006338--P:chromatin remodeling
GO:0030466--P:chromatin silencing at silent mating-type cassette
GO:0032508--P:DNA duplex unwinding
GO:0000070--P:mitotic sister chromatid segregation
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0060303--P:regulation of nucleosome density
GO:0006351--P:transcription, DNA-templated
|
