dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0000575
Uniprot Accession O14111; PSD3_SCHPO;
Genbank Protein ID NP_594016.2;
Genbank Nucleotide ID NM_001019442.2;
Protein Name Phosphatidylserine decarboxylase proenzyme 3
Protein Synonyms/Alias
Gene Name psd3
Gene Synonyms/Alias SPAC31G5.15;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)
May be involved in the regulation of phospholipid biosynthesis and interorganelle trafficking of phosphatidylserine (By similarity). Together with psd1 and psd2, responsible for the majority of phosphatidylethanolamine synthesis.
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
39DNVESCLSGDESNDScurated22817900
Sequence
(Fasta)
MPFTKSCRSA NTLRKGIKNG KLILKIIVND IDNVESCLSG DESNDSKKSS ASFYMKLKYG 60
SYRALADNIL STDENRKEDI AVFDVPLPNG LQIDTFTLCL YRKSKWKKQI VGEAYIGIQA 120
LLLSTNPDET CKYPVISPPS GRNKENQSPS HQICNLSLKW IIYDPEDADA DSKTLAKAWL 180
QQIKMNQTSI DPMSNISKSL KELEVDNVES DLEDSSFIAE PDSSIPPSES SVSISTDTGK 240
ETPPSKSKKS SNQPYVSIGE GNSDLLGFVF LEIISVSNLP PLKNVFRTGF DMDPFVITAF 300
SKNIFRTKWL RHNLNPVYNE KFLFEVGAFE SNYDLVFKVV DHDKMSLNDS IAVGSFNVQS 360
IINSSAQVDP ETGLYSFNIE TSSPSQDTSS KAEDSPTVQK IADDFSSAVG KDLRTDIIEQ 420
IIPLTLCCKH DFSTPRDVKL SFKAMFFPIA ALRQKFWRVM LAQYGDIEDG HIGKLGMYAV 480
LDTLGSNIPN SMVDDIYTEL SSKNHDDTSD SITVDEAVIC LERLVDLVCH QDQQATQTPQ 540
SPSSNEESGP GTPTQTSDQY EDSEDSRNFP SKLYLVYLSN CPLCLKFKLS KVNQQKATVH 600
LATCASHDWK RVDRLMMTSY VSLNQAQRRW FSKAFAKVVY GSSKVGSTSA TTLVQNRQTG 660
QIQEEKMNAY VRIGIRLLYR GIRNRRIEGS KVKKILRSLT LKQGMKYDSP ISVKEIKPFI 720
RFFDLNMNEV DMPVGGFKTF NEFFYRKLKP GSRPCAFPDN PDILVSPADS RIVAYECIEK 780
ATTYWIKGTE FTVERLLGYS NEAQRFVGGS ICISRLAPQD YHRFHSPVNG CIGPITKIEG 840
QYYTVNPMAI RSYLDVFGEN VRVLIPIDSN EFGKVMLVAV GAMMVGSTVL TVDEGKIVQR 900
SDELGYFKFG GSTVITLFEP NVTSFDEDLL RNSKTKIETL VKMGERIGQK IDPNKPTDAE 960
DHSKSDS 968
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0210--Decarboxylase
KW-0333--Golgi apparatus
KW-0444--Lipid biosynthesis
KW-0443--Lipid metabolism
KW-0456--Lyase
KW-0594--Phospholipid biosynthesis
KW-1208--Phospholipid metabolism
KW-0597--Phosphoprotein
KW-0670--Pyruvate
KW-1185--Reference proteome
KW-0926--Vacuole
KW-0865--Zymogen

Interpro

IPR000008--C2_dom
IPR003817--PS_Dcarbxylase

PROSITE

PS50004--C2

Pfam

PF00168--C2
PF02666--PS_Dcarbxylase

Gene Ontology

GO:0032153--C:cell division site
GO:0005829--C:cytosol
GO:0000329--C:fungal-type vacuole membrane
GO:0000139--C:Golgi membrane
GO:0005795--C:Golgi stack
GO:0004609--F:phosphatidylserine decarboxylase activity
GO:0005543--F:phospholipid binding
GO:0006656--P:phosphatidylcholine biosynthetic process
GO:0006646--P:phosphatidylethanolamine biosynthetic process