dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000573
Uniprot Accession O14104; LYS12_SCHPO;
Genbank Protein ID NP_594004.1;
Genbank Nucleotide ID NM_001019430.2;
Protein Name Homoisocitrate dehydrogenase
Protein Synonyms/Alias
Gene Name lys12
Gene Synonyms/Alias SPAC31G5.04;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
81ALFGAVQSPTHKVAGdbPTM 3.0;UniProt;curated18257517; 16381945; 23193290; 22817900
91HKVAGYSSPIVALRKdbPTM 3.0;UniProt18257517; 16381945; 23193290
Sequence
(Fasta)		MSATRRIVLG LIPADGIGKE VVPAARRLME NLPAKHKLKF DFIDLDAGWG TFERTGKALP 60
ERTVERLKTE CNAALFGAVQ SPTHKVAGYS SPIVALRKKM GLYANVRPVK SLDGAKGKPV 120
DLVIVRENTE CLYVKEERMV QNTPGKRVAE AIRRISEEAS TKIGKMAFEI AKSRQKIRES 180
GTYSIHKKPL VTIIHKSNVM SVTDGLFRES CRHAQSLDPS YASINVDEQI VDSMVYRLFR 240
EPECFDVVVA PNLYGDILSD GAASLIGSLG LVPSANVGDN FVMSEPVHGS APDIAGRGIA 300
NPVATFRSVA LMLEFMGHQD AAADIYTAVD KVLTEGKVLT PDLGGKSGTN EITDAVLANI 360
HN 363
Keyword

KW-0002--3D-structure
KW-0028--Amino-acid biosynthesis
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0457--Lysine biosynthesis
KW-0460--Magnesium
KW-0464--Manganese
KW-0479--Metal-binding
KW-0520--NAD
KW-0560--Oxidoreductase
KW-0597--Phosphoprotein
KW-1185--Reference proteome
Interpro

IPR019818--IsoCit/isopropylmalate_DH_CS
IPR001804--Isocitrate/isopropylmalate_DH
IPR024084--IsoPropMal-DH-like_dom
PROSITE

PS00470--IDH_IMDH
Pfam

PF00180--Iso_dh
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005739--C:mitochondrion
GO:0047046--F:homoisocitrate dehydrogenase activity
GO:0000287--F:magnesium ion binding
GO:0051287--F:NAD binding
GO:0009085--P:lysine biosynthetic process
GO:0019878--P:lysine biosynthetic process via aminoadipic acid