dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000571
Uniprot Accession O14095; PLP1_SCHPO; Q8NIQ0;
Genbank Protein ID NP_001018268.1;
Genbank Nucleotide ID NM_001019813.2;
Protein Name Thioredoxin domain-containing protein plp1
Protein Synonyms/Alias Phosducin-like protein 1;
Gene Name plp1
Gene Synonyms/Alias SPAC2F3.12c;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)		 Inhibits early G-protein signaling events following pheromone stimulation. May help create heterodimerizable beta-tubulin by facilitating the efficient transfer of nascent beta-tubulin polypeptides to the folding apparatus (By similarity).
Phosphorylation Sites
 dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
272DELQNNQSDDSDFFEdbPTM 3.0;UniProt;curated18257517; 16381945; 23193290; 22817900
275QNNQSDDSDFFE---dbPTM 3.0;UniProt18257517; 16381945; 23193290
Sequence
(Fasta)		MTSFPASHGF GPRKRGYQMD LTNVQPVENK PAWISMKSPL EKEIANEYEA LKVTERKEDT 60
QDYNEPELHN SNDPTVDLYA DTYATQAATE SDSELEDALF SQLDEFDDTA YREQRLEMLK 120
KEFARVEAAK EKGHMQFLTV ENEREVMDFT LSSKKVVIHF YHPDFIRCKI IDSHLEKIAK 180
VHWETKFIRI EAANAPFLVV KLGLKVLPAV LCYVNSQLVD KIIGFADLGN KDDFETSLLE 240
FRLLKSSAID RLKEESSSNK SIYHDELQNN QSDDSDFFE
Keyword

KW-0143--Chaperone
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0539--Nucleus
KW-0589--Pheromone response
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0734--Signal transduction inhibitor
Interpro

IPR012336--Thioredoxin-like_fold
IPR013766--Thioredoxin_domain
PROSITE
Pfam

PF00085--Thioredoxin
Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0045454--P:cell redox homeostasis
GO:0009968--P:negative regulation of signal transduction
GO:0006457--P:protein folding
GO:0019236--P:response to pheromone