dbPAF Protein Information
| Tag | Content |
|---|---|
| dbPAF ID | dbPAF-0000570 |
| Uniprot Accession | O14093; VPS54_SCHPO; |
| Genbank Protein ID | NP_594389.1; |
| Genbank Nucleotide ID | NM_001019811.2; |
| Protein Name | Vacuolar protein sorting-associated protein 54 |
| Protein Synonyms/Alias | |
| Gene Name | vps54 |
| Gene Synonyms/Alias | SPAC2F3.10; |
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast) |
| NCBI Taxa ID | 284812 |
| Functional Description (View all) |
Involved in retrograde transport from early and late endosomes to late Golgi by linking the vesicle through the t-SNARE TGL1 to the Golgi, leading to the membrane fusion between late Golgi and endosomal vesicles. Seems also to be involved in protein transport from Golgi to the plasma membrane and is required for the integrity of the actin cytoskeleton (By similarity). |
| Phosphorylation Sites |
dbPAF PTMs: 7 |
| Sequence (Fasta) | MERISSAPSI SLGYPPTESS AHLAPSFSDS ATSTLSFKSL LEDPVNPIRP VYTPTRTEIT 60 PVTLSPIPIT PVREFQPYLH EISQEYARYS KQKRASLRRY LEKHGKLEGS MKESSINGSL 120 LRRSSVSTIL RPASESSYPN SNSETITYDI DDNVNPSSSL VDNFSISSVP SVFFQSDFNL 180 DDPQIFDVVS EHIDITQTSD APNSNRNLLL NNSMLQEKIS WYLDTVELHL LQEIENASDS 240 FPMIIDNLKQ LKKETRDNVE ETKHLLEKLT EVNVMCDRHM DAISSEELAC HQLTQLKKVV 300 QTLEDIYSEH KKVSEDVKDQ RFLEAINGIN SIVTQLKKKS TELNVDLLSL PSVKSLREEH 360 KVLYHTVSQS VVQQFSKFLT SDMHKFSTIL DSNELKDIYL SKNRLIPSVT KSLPSAMEFD 420 ADFLHEVDVC IDCLTLTDSL QAALTLYKTA VFEAFENLAQ QYFTDGVEMR SVRKSSDLRR 480 SLSAASLSSL SDSSRRSSSA ANPFQSMSIT EFAEMLTNIY FSSLECLRRI RSQIKVLIDI 540 LSKKDTKQYH LSVILNDLMA TSSDVVTQQV TTINNLRFRV LDTYPPNNVI YLFSLHIIFH 600 NELESLCGIT QSSFIPTIMR QLLDWFKNFQ RYSTQKLASS FERELWEAIP VEPSCQDLAN 660 RVFECSGNTP VEWTRLLSPE AEKEDENHRV HHVKVSEDCT ATVSFGKQSL HIVRSSVTLL 720 ETLDDYGKLL AHFSRLAPEF QTGMLDMFRT LNSRVYQLIL GAGTVRSSGL SKVLGKHIAL 780 ASQTIALFQL SLNSMCRYLS RVTGTRLTNE TNKLDQDFTV HHLQIHDKFV SLMRERVAIS 840 CSQIASLSWD IDSPHGYIID LSKSLIKLYK VLHRYSQRDC VEVIPDVIRM FEDRLQLELT 900 DIARNPSKWP GVRIDLSYFY DMMASKCGYA GDRTLLEKFE RTPEQQEAA |
| Keyword | KW-0175--Coiled coil |
| Interpro | IPR012501--Vps54 |
| PROSITE | |
| Pfam | PF07928--Vps54 |
| Gene Ontology | GO:0005737--C:cytoplasm |