dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0000557
Uniprot Accession O14045; TPT1_SCHPO;
Genbank Protein ID NP_594515.2;
Genbank Nucleotide ID NM_001019944.2;
Protein Name Putative tRNA 2'-phosphotransferase
Protein Synonyms/Alias
Gene Name SPAC2C4.12c
Gene Synonyms/Alias
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)
Catalyzes the last step of tRNA splicing, the transfer of the splice junction 2'-phosphate from ligated tRNA to NAD to produce ADP-ribose 1''-2'' cyclic phosphate.
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
237VLLDAKASPKNNRSDcurated22817900
Sequence
(Fasta)
MYKNMNSHEL IEESNNSGTP ATKSSSKPTK KIRPRNDLVH YSKALSKVLR HTAKANGLQI 60
REDGYIEVDS ILKLPQFRGM GMELLLSIVK GNDKKRFTME EVEGVLYIRA NQGHSIKAVQ 120
VPMARIDNAS SIPKVVHGTK KELWPVISKQ GLSRMKRNHI HCATGLYGDP GVISGIRKSC 180
TLYIYIDSAK AMQDGVEFYR SENGVILTEG VNGLLSSKYF SRVETSDGEV LLDAKASPKN 240
NRSDESDQSD PESIDPFCDN LQALSMHELE LLEEKHSNFG YSEGIIKGKM QVAQSGFDDG 300
FKHGSRLGFQ MGKTIGTLKA KLYIFEENEQ MEILKQELDR LQESAEFHIF VANHKEEILK 360
CIREK 366
Keyword

KW-0181--Complete proteome
KW-0520--NAD
KW-1185--Reference proteome
KW-0808--Transferase
KW-0819--tRNA processing

Interpro

IPR019191--Essential_protein_Yae1_N
IPR002745--Ptrans_KptA/Tpt1

PROSITE
Pfam

PF01885--PTS_2-RNA
PF09811--Yae1_N

Gene Ontology

GO:0005634--C:nucleus
GO:0000215--F:tRNA 2'-phosphotransferase activity
GO:0006388--P:tRNA splicing, via endonucleolytic cleavage and ligation