dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000550
Uniprot Accession O14019; HAL4_SCHPO;
Genbank Protein ID NP_594866.1;
Genbank Nucleotide ID NM_001020295.2;
Protein Name Serine/threonine-protein kinase hal4
Protein Synonyms/Alias Halotolerance protein 4;Serine/threonine-protein kinase ppk10;
Gene Name hal4
Gene Synonyms/Alias ppk10;sat4;SPAC29A4.16;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)		 Promotes K(+) uptake, by the potassium transporter trk1-trk2, which leads to the subsequent cellular resistance to toxic cations such as Na(+), Li(+) and Ca(2+).
Phosphorylation Sites
 dbPAF PTMs: 5
PositionPeptidesSourceReferences ( PMIDs )
215TRLQRIFSQNSVSRQdbPTM 3.0;SysPTM 2.0;curated18257517; 16381945; 23193290; 19366988; 22817900
218QRIFSQNSVSRQNSRdbPTM 3.0;UniProt18257517; 16381945; 23193290
238AVANTEETNSTGGSEdbPTM 3.0;UniProt18257517; 16381945; 23193290
241NTEETNSTGGSETGGdbPTM 3.0;UniProt18257517; 16381945; 23193290
299KDFLAGNSKKREEERdbPTM 3.0;SysPTM 2.0;UniProt;curated18257517; 16381945; 23193290; 19366988; 22817900
Sequence
(Fasta)		MGEKDKLHEI SSKFASLGLG SLKSTPKARE TTEPPPPSSQ QPPSTPNGKE AASPSALKQN 60
VRPSLNSVQQ TPASIDAVAS SSNVSLQSQQ PLSKPVVSSK PNQTTAMPPP SNNPSRHVSS 120
TSNKPAAVSP NPAAHHAELP SGSVPPSASV SRANSTATTT PHKAGVVSNP AAANVHVLSV 180
AASPNPSTPS NGPAPVSTTA TPSRNPVTRL QRIFSQNSVS RQNSRTGRGA AVANTEETNS 240
TGGSETGGAA NSSSTSNPSS AKWSRFTVYD DASHTHQLRP ARRQEKLGKM LKDFLAGNSK 300
KREEERIAKE AADAQHQLSL VQSWINGYGQ EKLADKKDPA KVSASFVEKY GRCQEVIGRG 360
AFGVVRIAHK VDPQNSGSET LYAVKEFRRK PAESQKKYTK RLTSEFCISS SLRHPNVIHT 420
LDLIQDGKGD YCEVMELCSG GDLYTLIMAA GRLEPMEADC FFKQLMRGVD YLHDMGVAHR 480
DLKPENLLLT VSGSLKITDF GNGECFRMAW EKEAHMTCGL CGSAPYIAPE EYTESEFDPR 540
AVDVWACGVI YMAMRTGRHL WRVAKKSEDE YYSRYLMDRK NESGYEPIEM LERSRCRNTL 600
YNILHPNPTY RLTAKQIMKS EWVRSITLCE AGNAGL 637
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase
Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR002290--Ser/Thr_dual-sp_kinase
IPR008271--Ser/Thr_kinase_AS
PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
Pfam

PF00069--Pkinase
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0005524--F:ATP binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0030003--P:cellular cation homeostasis
GO:0071473--P:cellular response to cation stress
GO:0035556--P:intracellular signal transduction
GO:0006468--P:protein phosphorylation