dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000538
Uniprot Accession O13939; AP3B_SCHPO;
Genbank Protein ID NP_593796.1;
Genbank Nucleotide ID NM_001019225.2;
Protein Name AP-3 complex subunit beta
Protein Synonyms/Alias Adaptor-related protein complex 3 subunit beta;Beta-3-adaptin;Clathrin assembly protein complex 3 beta large chain;Clathrin assembly protein large beta chain;
Gene Name apl6
Gene Synonyms/Alias SPAC23H3.06;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)		 Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. Beta adaptin is a subunit of the plasma membrane adaptor (By similarity).
Phosphorylation Sites
 dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
638GNIYSNNSPGVKALSdbPTM 3.0;UniProt;curated18257517; 16381945; 23193290; 22817900
645SPGVKALSSDNFKRDcurated22817900
Sequence
(Fasta)		MSNLSFFQTL SGLAENAKQI AKSSSLSFEE NELSHSDLLR LLNSNSDAGK LEAINFILAQ 60
MMHGENMSLY FPDVVKLVAS ENPEIRRLVH IYLLQYAEFN PDLALLSVNT VQKTLYDKNP 120
LTRSTAIRVM SSIRVPAING IVLLAIQQCI TDTADRVRQS AALAITKCYS LDPSYKSQLE 180
EHIKTLLSDN SPIVVPAALF TFEVVCPEKL EIIHPYYHRI CTLFPQMNDW DKVVALKTLV 240
RYARLTLPEP STPSTHSDLK ELLESIKSCF FSLLPSTIIA GARAFYYLAP SNQMHLIVEP 300
LLQLLLEKPI VRTTTLRYIS QIVYKTPELF KNHIKSFFLI ASDSDDTCLL KINILSRLLD 360
AQNSSQILPE LLYYINSHPN PSVASTAVKA LGDFASANIS MAPSCLNTLL LLLKSHNSLI 420
VTEAASSLRL LIHNDPKEIY LQYLAATYET LEVPRAKSVT LWLISEHILI IPRLVPDVLR 480
IAVKTFADET LEVKYQILEL SVRLYVLSHS EEKQNDLESR DDVVSLLFNY VLSLIHFDMS 540
YDLRDRARFY KELASTPSSE FTRRIVLESK GNSQKEIIAS RDYCIGTASL CLNEDVMGYE 600
PIPNWADVSD LPPDSVREGI KDVLPINPHT GNIYSNNSPG VKALSSDNFK RDFGDTNAIN 660
RPKFVGQQTL EEFYASETSE SSEGEYETST SESEDEETDD TSQEEDNEKN STPDEDTENN 720
NTSSISTKSI MDRPLTEPEP NYWQS 746
Keyword

KW-0181--Complete proteome
KW-0968--Cytoplasmic vesicle
KW-0472--Membrane
KW-0597--Phosphoprotein
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
Interpro

IPR026740--AP3_beta
IPR026739--AP_beta
IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR002553--Clathrin/coatomer_adapt-like_N
PROSITE
Pfam

PF01602--Adaptin_N
Gene Ontology

GO:0030123--C:AP-3 adaptor complex
GO:0030665--C:clathrin-coated vesicle membrane
GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0006896--P:Golgi to vacuole transport
GO:0006886--P:intracellular protein transport