dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0000536
Uniprot Accession O13930; SEC2_SCHPO;
Genbank Protein ID NP_593182.1;
Genbank Nucleotide ID NM_001018578.2;
Protein Name Rab guanine nucleotide exchange factor sec2
Protein Synonyms/Alias GDP-GTP exchange factor sec2;
Gene Name sec2
Gene Synonyms/Alias SPAC23C4.10;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)
Guanyl-nucleotide exchange factor for ypt2. Catalyzing the dissociation of GDP from ypt2 and promotes the binding of GTP (By similarity).
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
75AKLSAKKSFDEELVKdbPTM 3.0;SysPTM 2.0;UniProt;curated18257517; 16381945; 23193290; 19366988; 22817900
Sequence
(Fasta)
MPDVSNVRVK PNQHPYEKEV NGKLMSQEEI LSQKLVAAIE RQAALDDKYA TEVHRNEALS 60
ERIRELEAKL SAKKSFDEEL VKFHNLEEKL QLTETKCRNA ESEKSRVENE LEDLTSSLFE 120
EANRMVANAR KETVASEKRV NQLKKQLVDA ETLLSSTQHQ LTELKDVMHS MSDSHEQNNA 180
LHPPLSRTTS FVADNVSVGS FASSTSGLDI LTGTSARESL DAKEISSDKH LNISGERPAT 240
FPNPTFIEGS DERRSASSLG HRTNNNQNQL IRFSTQIRSS STSPPRSPLI ISDSPSSSII 300
HNPHPTHPSA SAMNYMNPCF LEFHAFFNYP MKFARSRSAY STSANYSNTP PRNTVTPSTA 360
RSSTLSQNPS SSSNSIPLIS RNLRDFSFFK RCLEEDIEPT LRLDHASGLS WLTRRSVFTA 420
ILESSLIINP LHSTSLLSSQ PCSLCGFNRT QPLRQFEFRS RPDSTSHASC TYCVARLRSV 480
CNFVAFLHQI CKGVWSSCSL EKAWDECLKK REAMFLSRVG LAKELEG 528
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0344--Guanine-nucleotide releasing factor
KW-0597--Phosphoprotein
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport

Interpro

IPR009449--Sec2_N

PROSITE
Pfam

PF06428--Sec2p

Gene Ontology

GO:0032153--C:cell division site
GO:0051286--C:cell tip
GO:0005622--C:intracellular
GO:0005085--F:guanyl-nucleotide exchange factor activity
GO:0006887--P:exocytosis
GO:0006886--P:intracellular protein transport
GO:0043547--P:positive regulation of GTPase activity