dbPAF Protein Information
| Tag | Content | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| dbPAF ID | dbPAF-0000530 | ||||||||
| Uniprot Accession | O13907; ACL2_SCHPO; | ||||||||
| Genbank Protein ID | NP_593246.1; | ||||||||
| Genbank Nucleotide ID | NM_001018643.2; | ||||||||
| Protein Name | Probable ATP-citrate synthase subunit 2 | ||||||||
| Protein Synonyms/Alias | ATP-citrate (pro-S-)-lyase 2;Citrate cleavage enzyme subunit 2; | ||||||||
| Gene Name | SPAC22A12.16 | ||||||||
| Gene Synonyms/Alias | |||||||||
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast) | ||||||||
| NCBI Taxa ID | 284812 | ||||||||
| Functional Description (View all) |
ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA. Has a central role in de novo lipid synthesis (By similarity). | ||||||||
| Phosphorylation Sites |
dbPAF PTMs: 1
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| Sequence (Fasta) | MSAKSIREYD GKAVLAYWLN RSPSISKEEY KTVSATPAVQ LAQIQFPLPT LVIPAESTTY 60 REVVEDVFAK VEQEHPWVKE TKLVAKPDQL IKRRGKSGLL KLNATWDEAK EWIRERAGKN 120 QKVQHAVGYL TTFLVEPFVP HPPNTEYYIN INSVREGDWI LFCNEGGVDV GDVDAKARKL 180 LVPVRLSEFP SRATIASTLL SDIPVEQHES LVDFIIRLYS VYVDCQFTYL EINPLVVIPT 240 AKGADVFYLD LAAKLDQTAE FECGAKWAVA RAPESLGIKT SGEESGAINA DHGPPMVFPA 300 PFGRELSKEE AYVQGLDAKT GASLKLTILN AEGRVWNLVA GGGASVVYAD AVAVNGAADE 360 LANYGEYSGA PTDGQTYEYA KTVLDLMTRG EPRADGKVLF IGGGIANFTS PAVTFRAIAR 420 ALGDYKDKLH AHKVSIWVRR AGPNYQEGLR VIREAGKKFD LPLKVYGPEC HISGIVPMGL 480 GKAPVEAEWQ MA 493 |
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| Keyword | KW-0012--Acyltransferase |
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| Interpro | IPR013650--ATP-grasp_succ-CoA_synth-type |
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| PROSITE | PS01217--SUCCINYL_COA_LIG_3 |
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| Pfam | |||||||||
| Gene Ontology | GO:0005737--C:cytoplasm |