dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0000527
Uniprot Accession O13900; SA114_SCHPO;
Genbank Protein ID NP_593239.1;
Genbank Nucleotide ID NM_001018636.2;
Protein Name Pre-mRNA-splicing factor sap114
Protein Synonyms/Alias Spliceosome-associated protein 145;
Gene Name sap114
Gene Synonyms/Alias SPAC22A12.09c;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)
Involved in pre-mRNA splicing. May be involved in endoplasmic reticulum-associated protein degradation (ERAD) and required for growth at low and high temperatures (By similarity).
Phosphorylation Sites
dbPAF PTMs: 4
PositionPeptidesSourceReferences ( PMIDs )
206LIREPISSPEQELREcurated22817900
350GGISSTTSVSPAAQAcurated22817900
358VSPAAQASPVLSTTTcurated22817900
363QASPVLSTTTQPKVQdbPTM 3.0;SysPTM 2.0;curated18257517; 16381945; 23193290; 19366988; 22817900
Sequence
(Fasta)
MSSLMEFQDR NTTNNETEHQ KSITDQSSSV PAGVILPPPA IREIIDKSAS YVARNGPAFE 60
EKIRQNEQAN TKFAFLHAND PYHPYYQHKL TEAREGKLKS HATGLSTQKT STLARPIQKP 120
IEATIPAPSP YLFSEPLPSI SSLDLDVLRL TARYAAVRGS SFLVSLSQKE WNNTQFDFLK 180
PNNALYPYFM RIVQQYTSLI REPISSPEQE LRENVRDPYS LLSKIQPRVR WQSHMESQKK 240
KQKEEAEKEK LEYAQIDWND FVVVEVIQFT KSDEHAKLAK PTNLADLQTA TLEQKSAMFT 300
MPDQNYTIEE APPTAEPWEP ISAPKKQEFG VSLPPSLASP EKGGISSTTS VSPAAQASPV 360
LSTTTQPKVQ KPVPKAFQPK VPMEISPFSG ELVPATELEE HMRLKLLDPR WQEQRKVEES 420
RKSTLNLENV NVAANMKRLV SQRTDLFDVQ NGVEISQEEI ERRKRAATQS AWGATPTNKR 480
R 482
Keyword

KW-0143--Chaperone
KW-0181--Complete proteome
KW-0507--mRNA processing
KW-0508--mRNA splicing
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0747--Spliceosome

Interpro

IPR022030--SF3A1
IPR000061--Surp

PROSITE

PS50128--SURP

Pfam

PF12230--PRP21_like_P
PF01805--Surp

Gene Ontology

GO:0071013--C:catalytic step 2 spliceosome
GO:0005634--C:nucleus
GO:0005681--C:spliceosomal complex
GO:0005686--C:U2 snRNP
GO:0071004--C:U2-type prespliceosome
GO:0003723--F:RNA binding
GO:0000389--P:mRNA 3'-splice site recognition
GO:0045292--P:mRNA cis splicing, via spliceosome