dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0000525
Uniprot Accession O13898; PMT1_SCHPO;
Genbank Protein ID NP_593237.1;
Genbank Nucleotide ID NM_001018634.2;
Protein Name Dolichyl-phosphate-mannose--protein mannosyltransferase 1
Protein Synonyms/Alias
Gene Name ogm1
Gene Synonyms/Alias oma1;SPAC22A12.07c;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)
Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins. Required for normal cell growth and septum formation. Shown to actively O-mannosylate wsc1.
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
451GTVETLNTKFRLIHVdbPTM 3.0;UniProt18257517; 16381945; 23193290
Sequence
(Fasta)
MDKQSTFQDP KEKHRIQRDV KLSRPRKRFS FLDYVVVIFL TVVAFCVRAQ RLMNPAKVVF 60
EELRYYNYAV DYVNNKLLMD VYPPLGKLLF SLVAALTGNK YELNTLDEPG QQYPFTDVAY 120
SMRLFTCLLG SLLVPLMYGT VYFPTKSKTA ASLAALFVIF DNGLITMSRY IMIEIPALYF 180
MSLTAFYWSV YEAQQKRPFS LRWHTSLLST GVALGLALST KLSAMFTFGW LLILAAFHLW 240
NLLGDLSVPM YRIVKHLFSY IFYLIGVPIT VYLAVFAVHS HIAYKASVAD AFLPPEHRHA 300
LAGNRFDDQF ADVAYGSLVT IRNAIPEHGY LHSSELLYPE GTEQQIISLV DEPNQNALWI 360
IEHEHSQDNN RSNIELLKDG SVVRLRHVMT GRALHSHEHK PIVSNNDWQL EASAYGGFGF 420
EGDANDLFRI QILEKKSKHA TSNGTVETLN TKFRLIHVFA NCELMSSHRR FPDWGDYQRE 480
VTCCRNCVER STTWFIESNY HDGLPSDSRK ITYRKPGFLE SFVEHNKLMW LKDRKMGDGH 540
VYESSALTWP LLLGPLRFFY EQHLQVFFMG NPFVWYSVIS LVAFFVIVQI FCLARWNLGY 600
NDFGPSAFHY NYNIGKFVVA WLLHWAPYIL ETDRVFLYHY LPALYFGIAA LGVSWSFLGN 660
AVFGNRTAYK ALSVIIMALM FLVYRLYSPF TYMTTLTKSS CRALELKGSW NFHCNTYLDN 720
LSDYKFSSDA GETYFEKAAP HPFVYSEDTA KKSEGDTPLN KNLNDYYPSW DQRVEAGYKL 780
AAQQKAEQEA REAAEKAASE AAERSSSEAA ASSSSESVAA ASVEAERLAM EADEFNGASE 840
TVDGASVEAE RSAMEAAALN NAAESTEVVG SSPESVASEQ EENVAESAQA RVE 894
Keyword

KW-0181--Complete proteome
KW-0256--Endoplasmic reticulum
KW-0325--Glycoprotein
KW-0328--Glycosyltransferase
KW-0472--Membrane
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR027005--GlyclTrfase_39-like
IPR003342--Glyco_trans_39/83
IPR016093--MIR_motif
IPR027004--PMT1/PTM5
IPR032421--PMT_4TMC

PROSITE

PS50919--MIR

Pfam

PF02815--MIR
PF02366--PMT
PF16192--PMT_4TMC

Gene Ontology

GO:0012505--C:endomembrane system
GO:0005789--C:endoplasmic reticulum membrane
GO:0016021--C:integral component of membrane
GO:0031965--C:nuclear membrane
GO:0004169--F:dolichyl-phosphate-mannose-protein mannosyltransferase activity
GO:0000032--P:cell wall mannoprotein biosynthetic process
GO:0044845--P:chain elongation of O-linked mannose residue
GO:0035269--P:protein O-linked mannosylation