dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0000523
Uniprot Accession O13880; VHT1_SCHPO;
Genbank Protein ID NP_594801.1;
Genbank Nucleotide ID NM_001020229.2;
Protein Name Vitamin H transporter 1
Protein Synonyms/Alias H(+)/biotin symporter vht1;
Gene Name vht1
Gene Synonyms/Alias SPAC1B3.16c;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)
Involved in uptake of biotin and desthiobiotin with the concomitant entry of protons.
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
288ASKEHRKSLSSFIPLdbPTM 3.0;SysPTM 2.0;curated18257517; 16381945; 23193290; 19366988; 22817900
Sequence
(Fasta)
MASEWPETSR ASSVEENPKL NIPEIVESVS DSKPSLKNQF STTVIDSSDL NVFNDGAETT 60
VKEQEFTSSE LRRLQKLRLK MDLRIIPCLW ILYFLSCCLR FTVSLSFTMN TAQGHSLIQT 120
LSGYSAHYLA LGLALFYVGY IIFEVPSNLM MAFIEPRIWV SRIQLTIGVV GACHAVLGTK 180
HGNAQSYVAL RFFLGVAESG LWPGLAYYMS RWYRGKHLGK RIGWYYTAAQ IAAAAVSLVS 240
AGFQKMDGAR GLYGYQWMFL IWGVVAIAQA LSIPWWLPAV ASKEHRKSLS SFIPLPKWMK 300
TLSPQRIGFL TPADKSLHSR YIAEMNVGKR WQWSDLLKSC LDLRVWPFIL MYFGIVGVGN 360
GIFNYCTLII EEINPSFSGI DISLLNAPIW LADALGIVTV MPLYDRFHKK FSFFTGSCLI 420
IIAGLAVANY APRAWSRYGG LLMIGFGLGP TVPICMAWCS ASMAKTYGDV GVASSLALVT 480
GLGNLGSVVT TYALYSGWPG DPTFRKSNDV CIALIGVSII ACGIEFLLDK TGFGQFNASF 540
NNHDHEVEDE QEMTDIKPAL PSSQQADA 569
Keyword

KW-0092--Biotin
KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0769--Symport
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0813--Transport

Interpro

IPR011701--MFS
IPR020846--MFS_dom

PROSITE
Pfam

PF07690--MFS_1

Gene Ontology

GO:0005794--C:Golgi apparatus
GO:0005887--C:integral component of plasma membrane
GO:1901603--F:biotin transmembrane transporter activity
GO:1901604--F:dethiobiotin transmembrane transporter activity
GO:0015295--F:solute:proton symporter activity
GO:0044756--P:biotin import into cell
GO:0044757--P:dethiobiotin import into cell
GO:0015992--P:proton transport
GO:0035461--P:vitamin transmembrane transport