dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000516
Uniprot Accession O13853; ITS3_SCHPO;
Genbank Protein ID NP_594429.1;
Genbank Nucleotide ID NM_001019858.2;
Protein Name Phosphatidylinositol 4-phosphate 5-kinase its3
Protein Synonyms/Alias 1-phosphatidylinositol 4-phosphate kinase;Diphosphoinositide kinase;PIP5K;PtdIns(4)P-5-kinase;
Gene Name its3
Gene Synonyms/Alias SPAC19G12.14;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)		 Involved, together with the calcineurin ppb1, in cytokinesis.
Phosphorylation Sites
 dbPAF PTMs: 4
PositionPeptidesSourceReferences ( PMIDs )
175QQPPNDRSTLSSSQKcurated22817900
176QPPNDRSTLSSSQKAcurated22817900
180DRSTLSSSQKAKRPLcurated22817900
545VSQHRVPSINGNESHcurated22817900
Sequence
(Fasta)		MKIDSNGIVN PHSITNEIPS YDEKQAVDLN GNAFAPNGTF QKKDLISHKN DFERTMRHDV 60
LHTNPKIEVR SETHIYEPND SLFKENQDFP SNPTAHSPSS SSNDSVITAT GVPDGILRDS 120
PIVSALEPPS SNSSSSPQLQ NLKHQLSSPQ PSRAPIDRSS SNPVTSSQQP PNDRSTLSSS 180
QKAKRPLKRS YSEKNSSNAE PSGSRSGDRG TNVSTSGSLL DGIPPDIGSA SWAEAVKQKR 240
VNMRRRREEL DDECVLVGTR VSEGHENYVT AYNMLTGIRV GVSRCQAKMD RELTPADFTA 300
RHKFTFDITG NELTPSAKYD FKFKDYAPWV FRHLRQLFHL DAADYLVSLT SKYILSELDS 360
PGKSGSFFYF SRDYRFIIKT IHHSEHKFLR EILYDYYEHV KNNPNTLISQ FYGLHRVKLP 420
FGRKIHFVVM NNLFPPHRDI HQTFDLKGST LGRELDENQP CQSPMCTMKD TNWIRRNMHL 480
QFGPLKRQIF LTQVKADIDM LSSLGIMDYS LLVGIHDLSR GNRDKIRNSI LSVYDPNVSQ 540
HRVPSINGNE SHSNVHVIRQ VVNSTGPVSL DQSCNLLPTD QFVERRNFMF YSDDGGFQAT 600
DENNEPGNFI FYIGIIDLLT KYSYVKRVEH LWKGINHSDS VISAVPPAEY ASRFYKFVES 660
SIKPTLLVLK PFPLKPQDGQ RVNKQQSVNA GNVRTNNKHG SLNNNTAPSS RNAKSTSAHK 720
SPKTEHRFPF PCRNVTTNTS SS 743
Keyword

KW-0067--ATP-binding
KW-0131--Cell cycle
KW-0132--Cell division
KW-0181--Complete proteome
KW-0418--Kinase
KW-0472--Membrane
KW-0547--Nucleotide-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0808--Transferase
Interpro

IPR023610--PInositol-4-P-5-kinase
IPR027483--PInositol-4-P-5-kinase_C
IPR002498--PInositol-4-P-5-kinase_core
IPR027484--PInositol-4-P-5-kinase_N
IPR016034--PInositol-4P-5-kinase_core_sub
PROSITE

PS51455--PIPK
Pfam

PF01504--PIP5K
Gene Ontology

GO:0000935--C:barrier septum
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0016308--F:1-phosphatidylinositol-4-phosphate 5-kinase activity
GO:0005524--F:ATP binding
GO:0007049--P:cell cycle
GO:0051301--P:cell division
GO:0046488--P:phosphatidylinositol metabolic process
GO:0046854--P:phosphatidylinositol phosphorylation