| Tag |
Content |
| dbPAF ID |
dbPAF-0000507 |
| Uniprot Accession |
O13821; VPS27_SCHPO;
|
| Genbank Protein ID |
NP_593787.1;
|
| Genbank Nucleotide ID |
NM_001019216.2;
|
| Protein Name |
Vacuolar protein sorting-associated protein 27 |
| Protein Synonyms/Alias |
Suppressor of ste12 deletion protein 4; |
| Gene Name |
sst4 |
| Gene Synonyms/Alias |
vps27;SPAC19A8.05c; |
| Organism |
Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast) |
| NCBI Taxa ID |
284812 |
Functional Description
(View all) |
Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane.Functional Description
Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane. |
Phosphorylation Sites
|
dbPAF PTMs: 3 |
Sequence
(Fasta) | MSRWWNSNSQ FASDIEKATS ETLPAGSEEI SLYLEISDQI RSKSVDPKFA MRILKSRIDH 60
SNPNVQIMAL KLTDTCVKNG GSGFLLEIAS REFMDNLVSI LRSPAGIDED VKMVILRYIQ 120
SWALAVPDTN SPLSYIIHVY QNLKDGDYEF PEPSQNITSK FLDTETPPDW TDSEVCLRCR 180
TPFTFTNRKH HCRNCGGVFC NQCSSKTLSL PHLGINQPVR VCDSCYSLRT KPKGSKSRAR 240
NERKFHAKTR KTPSKPVTNN EDEDIKRAIE LSLKEMPQSR EPPSYERPSE ANVVISQDQH 300
LTEDEDEELK RAIAISLEEA QKSSQKDDNV TAPNNMNISY PSVPAHTVST DIRSSPFSGR 360
PSDNPSTLIS TADADNITLY ATLVQKLKKL PPGSIFTEYQ LQELHENMGV MRTRMMRSLG 420
ETMSKYNGLI QALQKLQTCM RLNDALIEQR LSSTYAHHYI DSSMDSNRSI EPEPDVISTV 480
RNSSTIPQAS SSSVPKIVVD SSPVTENPPS HSDVMGQKDT ISSYYSTDTD VSANVMGNRH 540
DEVVFSDTAS GEKNTKLNID ESTNYYNTDS IDKVGEPFDE ISSGYDDLMN GNDKQGNDIP 600
EVQEASLIEL
611Fasta Sequence
>O13821|sst4|Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
MSRWWNSNSQFASDIEKATSETLPAGSEEISLYLEISDQIRSKSVDPKFAMRILKSRIDHSNPNVQIMALKLTDTCVKNGGSGFLLEIASREFMDNLVSILRSPAGIDEDVKMVILRYIQSWALAVPDTNSPLSYIIHVYQNLKDGDYEFPEPSQNITSKFLDTETPPDWTDSEVCLRCRTPFTFTNRKHHCRNCGGVFCNQCSSKTLSLPHLGINQPVRVCDSCYSLRTKPKGSKSRARNERKFHAKTRKTPSKPVTNNEDEDIKRAIELSLKEMPQSREPPSYERPSEANVVISQDQHLTEDEDEELKRAIAISLEEAQKSSQKDDNVTAPNNMNISYPSVPAHTVSTDIRSSPFSGRPSDNPSTLISTADADNITLYATLVQKLKKLPPGSIFTEYQLQELHENMGVMRTRMMRSLGETMSKYNGLIQALQKLQTCMRLNDALIEQRLSSTYAHHYIDSSMDSNRSIEPEPDVISTVRNSSTIPQASSSSVPKIVVDSSPVTENPPSHSDVMGQKDTISSYYSTDTDVSANVMGNRHDEVVFSDTASGEKNTKLNIDESTNYYNTDSIDKVGEPFDEISSGYDDLMNGNDKQGNDIPEVQEASLIEL
|
| Keyword |
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0967--Endosome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0862--Zinc
KW-0863--Zinc-finger
|
| Interpro |
IPR008942--ENTH_VHS
IPR003903--UIM_dom
IPR002014--VHS_dom
IPR018205--VHS_subgr
IPR000306--Znf_FYVE
IPR017455--Znf_FYVE-rel
IPR011011--Znf_FYVE_PHD
IPR013083--Znf_RING/FYVE/PHD
|
| PROSITE |
PS50330--UIM
PS50179--VHS
PS50178--ZF_FYVE
|
| Pfam |
PF01363--FYVE
PF02809--UIM
PF00790--VHS
|
| Gene Ontology |
GO:0005829--C:cytosol
GO:0010008--C:endosome membrane
GO:0033565--C:ESCRT-0 complex
GO:0005634--C:nucleus
GO:0005628--C:prospore membrane
GO:0046872--F:metal ion binding
GO:0032266--F:phosphatidylinositol-3-phosphate binding
GO:0043130--F:ubiquitin binding
GO:0031321--P:ascospore-type prospore assembly
GO:0006897--P:endocytosis
GO:0045324--P:late endosome to vacuole transport
GO:0006900--P:membrane budding
GO:0045053--P:protein retention in Golgi apparatus
GO:0043328--P:protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
|
