dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000501
Uniprot Accession O13796; RCQ1_SCHPO; Q9P7G1;
Genbank Protein ID NP_594265.2;
Genbank Nucleotide ID NM_001019688.3;
Protein Name Ribosome quality control complex subunit 1
Protein Synonyms/Alias
Gene Name rqc1
Gene Synonyms/Alias SPAC1142.01;SPAC17G6.18;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)		 Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation. Rqc1 is essential for the recruitment of cdc48 to ribosomal subunits.
Phosphorylation Sites
 dbPAF PTMs: 7
PositionPeptidesSourceReferences ( PMIDs )
56KENNAINSEAEKSVSdbPTM 3.0;UniProt;curated18257517; 16381945; 23193290; 22817900
61INSEAEKSVSEEEQDdbPTM 3.0;UniProt18257517; 16381945; 23193290
63SEAEKSVSEEEQDEPdbPTM 3.0;UniProt18257517; 16381945; 23193290
110KRDLDNQSSDNEKLEdbPTM 3.0;UniProt;curated18257517; 16381945; 23193290; 22817900
111RDLDNQSSDNEKLEGdbPTM 3.0;UniProt;curated18257517; 16381945; 23193290; 22817900
121EKLEGLESSKNIDDDcurated22817900
122KLEGLESSKNIDDDIcurated22817900
Sequence
(Fasta)		MSSRALRKLQ RQRQTELLEE ALDSESDEDD EFSSTSGKKV VNVFEILEKE NNAINSEAEK 60
SVSEEEQDEP LVEGESPIVS TNKKAKNKKK KKKQQKKKKV TGKRDLDNQS SDNEKLEGLE 120
SSKNIDDDID EIEKAAAELK LKYREQDQVE HVAGVEESAT IPLDKELDEK LNKLLGVNIS 180
MLNPDLEIRK IFGRIVEKRS VNARHDNLRR KRHVLVQPQE GWPPLVRSGL GMKLTGQSQD 240
LECFFEITQS RAYQEVQETF EYYVQTYDPN NLLMLLRSHP FHIDTLLQVS EIIDQQGDHE 300
LSAELVARGL YAFDSILHPR FNLATGATRL PFAIPSNRRL FLCIWRYLQS LQSRGCWRTV 360
FEFCKALLQF DMSDPYAIGT CIDIYALRRR EFAWIIDFAN YLENSNKISD TPNMLYSSAL 420
AMFYVHGDTT DTRASMLAAF ERAPYMLSEL LDTLNISFTK SSIPSPQDPV QELHSAMYAL 480
YAKDSWSDPT VLAFINSILE KETVTLHDVE GQFAELTENL SRRVILLNEQ SLRKFLPQRI 540
LQGTILSFDP LPPDTYLSES QVFGRDISRR IASFLSDYLS RAREVNENEE EPPAHEFDLP 600
PAEQLLQQIE SEVGEESEDG TPVMTRLRSF FGSLFTSTNS ETEPAEESTE EMGQGD 657
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0597--Phosphoprotein
KW-1185--Reference proteome
Interpro

IPR006994--TCF25
PROSITE
Pfam

PF04910--Tcf25
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:1990112--C:RQC complex
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:1990116--P:ribosome-associated ubiquitin-dependent protein catabolic process