dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0000490
Uniprot Accession O13759; CSX1_SCHPO; Q09331; Q09335;
Genbank Protein ID NP_594243.1;
Genbank Nucleotide ID NM_001019666.2;
Protein Name RNA-binding post-transcriptional regulator csx1
Protein Synonyms/Alias
Gene Name csx1
Gene Synonyms/Alias SPAC17A2.09c;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)
Regulates global gene expression after oxidative stress. Interacts and stabilizes atf1 and pcr1 mRNAs after oxidative stress, thus controlling their turnover.
Phosphorylation Sites
dbPAF PTMs: 7
PositionPeptidesSourceReferences ( PMIDs )
42SDVNAPISPVVDEGKdbPTM 3.0;SysPTM 2.0;curated14633985; 18257517; 16381945; 23193290; 19366988; 22817900
54EGKSELVSPTLERLVdbPTM 3.0;SysPTM 2.0;curated14633985; 18257517; 16381945; 23193290; 19366988; 22817900
67LVAPFNCSPSSTPLQdbPTM 3.0;UniProt18257517; 16381945; 23193290
69APFNCSPSSTPLQDVdbPTM 3.0;UniProt18257517; 16381945; 23193290
291QPNQDLCSMDPLNTTdbPTM 3.014633985; 16381945; 23193290
455SVNFSTISPPPLSRSdbPTM 3.014633985; 16381945; 23193290
578NLGRERQSSLIDLRHcurated22817900
Sequence
(Fasta)
MSIDCLYRRS SLFDTSFVPL HSSIPATSKM SASNSDVNAP ISPVVDEGKS ELVSPTLERL 60
VAPFNCSPSS TPLQDVAGVG SKMSDTLWMG DLEPWMDATF IQQLWASLNE PVNVKVMRSK 120
ASSSETLISY CFVQFSSSAA AERALMKYNN TMIPGAHCTF KLNWATGGGI QHNNFVSRDP 180
EFSIFVGDLL PTTEDSDLFM TFRSIYPSCT SAKIIVDPVT GLSRKYGFVR FSSEKEQQHA 240
LMHMQGYLCQ GRPLRISVAS PKSRASIAAD SALGIVPTST SNRQPNQDLC SMDPLNTTVF 300
VGGLASNLSE KDLQVCFQPF GRILNIKIPF GKGCGFVQYS EKSAAEKAIN TMQGALVGTS 360
HIRLAWGHNT LPVSALSQSQ SQVSDEGFDR TLSANQIFGM NQSVIGANSG SSNSSGSSLK 420
SAPVSPRTAA AQSLLPNSVV SSINGMNSVN FSTISPPPLS RSASISPTLS GSGSGLTPLS 480
SHFPSAATGL VGGQVYPQSS VLQSSKINGS AKVQPSVKLP EWLQPFSGNN HNSFATQDLL 540
TRVSSLKLVD DEQPASLNGS AFQARASRPW NLGRERQSSL IDLRHELEQN ENGLEKSGFG 600
LNLRGRLPPR SYSTFNCTGQ YLQPSLRLSR DS 633
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0903--Direct protein sequencing
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0694--RNA-binding

Interpro

IPR012677--Nucleotide-bd_a/b_plait
IPR000504--RRM_dom

PROSITE

PS50102--RRM

Pfam

PF00076--RRM_1

Gene Ontology

GO:0005737--C:cytoplasm
GO:0000932--C:cytoplasmic mRNA processing body
GO:0010494--C:cytoplasmic stress granule
GO:0005829--C:cytosol
GO:0003729--F:mRNA binding
GO:0000166--F:nucleotide binding
GO:0070935--P:3'-UTR-mediated mRNA stabilization
GO:2000815--P:regulation of mRNA stability involved in response to oxidative stress