dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000478
Uniprot Accession O13718; VTC2_SCHPO;
Genbank Protein ID NP_594916.1;
Genbank Nucleotide ID NM_001020348.2;
Protein Name Vacuolar transporter chaperone 2
Protein Synonyms/Alias
Gene Name vtc2
Gene Synonyms/Alias SPAC14C4.11;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)		 Component of the vacuolar transporter chaperone (VTC) complex, which plays a role in vacuolar membrane fusion.
Phosphorylation Sites
 dbPAF PTMs: 3
PositionPeptidesSourceReferences ( PMIDs )
181GLSAPSNSVQVKPKHdbPTM 3.0;UniProt18257517; 16381945; 23193290
529RVLKQNMTPEPSQPSdbPTM 3.0;UniProt;curated18257517; 16381945; 23193290; 22817900
583GLLKPSTYGSFKHHGdbPTM 3.0;UniProt18257517; 16381945; 23193290
Sequence
(Fasta)		MRFSDSIEAG IYEPWRDKYM NYPELKHLLK TEEEAPSWGE NDESKFVSVM DAQLEKVYAF 60
HLEILKELNE SVDWVKSKVS ASQEPDGPPI SKEEAIKLLE RLDSCTETVK KLEKYTRLNL 120
TGFFKIVKKH DKLYPGYSLR PVFQVRLRAC PLGSVQFNPL LAEIFSLYNT LRDGLSAPSN 180
SVQVKPKHEH NVDYNSSMYR RRTFRFWVHP DNVMEVKTYI MRHLPVLYYS GKQGFDKDQN 240
GVSGILDPIS TCLYLDNSNF DLYSQNLERS EQAYSLRLHW YGKLTPKTDI IVERMVRQGS 300
TLSHSEDRFT IREKKVRELL SGRYDFRKVE DDHSTTASDQ KKKLIEDVEQ LIVDNHLQPV 360
LRSVYTRTAF QIPGDDEVRI NLDSDWVMIR EDSLDIERPC RDPEDWHRHD IDDADFPYKH 420
LRKGEYSRFP YSVLEIRECV RYDEDEPLWI SELRNSHLIS EIDGFSKYEH GVAILFEKYV 480
SLLPMWVFSM DQDIRKDLQE VYSHPEGSAG SRNVYIKRRN QRVLKQNMTP EPSQPSPLVN 540
RLKANEMHPV SEEPEDNREV YRNEHGDHFN FRSIPGLLKP STYGSFKHHG KTFVTPPHIK 600
KPEIPLRVSG PIKVEAKVWL ANERTFLKWL HVVVLLGSLA LALYNSAGER LGQAFGVVYT 660
LLAIFIGFYA WKLHAKRSQM IKSRSPAPMT DYWGPLIVGT ALAISLIVNM SFALKDAVYQ 720
NLIEPDRLLV KLFT 735
Keyword

KW-0143--Chaperone
KW-0181--Complete proteome
KW-0472--Membrane
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0926--Vacuole
Interpro

IPR003807--DUF202
IPR004331--SPX_dom
IPR018966--VTC_domain
PROSITE

PS51382--SPX
Pfam

PF02656--DUF202
PF03105--SPX
PF09359--VTC
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005783--C:endoplasmic reticulum
GO:0000329--C:fungal-type vacuole membrane
GO:0016021--C:integral component of membrane
GO:0033254--C:vacuolar transporter chaperone complex
GO:0006914--P:autophagy
GO:0016237--P:lysosomal microautophagy
GO:0006797--P:polyphosphate metabolic process
GO:0007034--P:vacuolar transport
GO:0042144--P:vacuole fusion, non-autophagic