dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000464
Uniprot Accession O13615; PRP46_SCHPO;
Genbank Protein ID NP_595604.1;
Genbank Nucleotide ID NM_001021499.2;
Protein Name Pre-mRNA-splicing factor prp5
Protein Synonyms/Alias Complexed with cdc5 protein 1;Pre-mRNA-processing protein 5;
Gene Name prp5
Gene Synonyms/Alias cwf1;pi024;SPBP22H7.07;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)		 Required for both cell cycle progression at G2/M and pre-mRNA splicing. Interacts genetically with the PRP4 kinase.
Phosphorylation Sites
 dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
88ALTVRADSENPSSQVdbPTM 3.0;SysPTM 2.0;curated18257517; 16381945; 23193290; 19366988; 22817900
Sequence
(Fasta)		MTEAKNISDD TDVLSLTTNS LRTSKTLFGA EFGSVTSFDD TVAQNLKRTY KEHLEYGSVL 60
GGTVGKRKNR HYEEDTIGSN ALTVRADSEN PSSQVITKFS DPNKKIAGQV SMQSLEKIKG 120
VPEAAHRIAG ESQASLVKRT LAEQIRPEWH APWTLMRVIS GHLGWVRCVD VEPGNQWFCT 180
GAGDRTIKIW DLASGVLKLT LTGHIATVRG LAVSPRHPYL FSCGEDKMVK CWDLETNKVI 240
RHYHGHLSGV YALKLHPTLD VLVTAGRDAV ARVWDMRTRQ NVHVLSGHKS TVASLAVQEF 300
DPQVVTGSMD STIRLWDLAA GKTLTTLTHH KKTVRALSLH PDEFTFASGS SDNIKHWKFP 360
EGAFMGNFEG HNAIVNTLSI NSDNVMFSGA DNGSMCFWDW KSGHKYQELQ SVVQPGSLDS 420
EAGIFASSFD KTGLRLITCE ADKSVKIYKQ VDNATPETHP NLPWTPSNLR RRY 474
Keyword

KW-0002--3D-structure
KW-0181--Complete proteome
KW-0903--Direct protein sequencing
KW-0507--mRNA processing
KW-0508--mRNA splicing
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0747--Spliceosome
KW-0853--WD repeat
Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00400--WD40
Gene Ontology

GO:0005634--C:nucleus
GO:0000974--C:Prp19 complex
GO:0005681--C:spliceosomal complex
GO:0045292--P:mRNA cis splicing, via spliceosome