dbPAF Protein Information
| Tag | Content |
|---|---|
| dbPAF ID | dbPAF-0000462 |
| Uniprot Accession | O13612; NEP2_SCHPO; Q9UTT9; |
| Genbank Protein ID | NP_595608.1; |
| Genbank Nucleotide ID | NM_001021503.2; |
| Protein Name | NEDD8-specific protease 2 |
| Protein Synonyms/Alias | Meiotically up-regulated gene 120 protein; |
| Gene Name | nep2 |
| Gene Synonyms/Alias | mug120;pi021;SPBC32H8.02c; |
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast) |
| NCBI Taxa ID | 284812 |
| Functional Description (View all) |
Protease that catalyzes two essential functions in the NEDD8 pathway: processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted proteins such as the pcu1, pcu2 and pcu4 cullins and other proteins (By similarity). Has a role in meiosis. |
| Phosphorylation Sites |
dbPAF PTMs: 2 |
| Sequence (Fasta) | MRSNSIFTKE IDSEAVKKSS NLRPPSTGSS NSNGSDTASP KKKKKGFFRS LFGSSSSGSK 60 SCGSPFTRIW LEYFEVSLRK NDVDHFRPGY WILDTNIDFF YEIMLRQVLL KRPKEESQQI 120 YLLRPAMVFF LAQAPNPLEI ESALPPAMFD ASFIFLPIND TNECGIESGS HWSLLVVSVE 180 KGLGWYYDSM SNGNTNDCNL AIKNLGILLK KEFRVRHMKT PQQINDCDCG LHVCENTRIL 240 MYRLLQKPYV PKVDMNLDHS VVDSVRLRKA LMEVITSLLA AYGSKVPKPS ETHTDPEKDK 300 KIFSKICKTE ELLELPTLSA VTSDSAQPHS LPASMPSSQP QSRSESLPLT HPNSEPNPKL 360 DSQPNSSPVR RPSLIKVKTA STSVLPTSIL QRPPSIVPRP ETAAIQHTQQ SIEIH 416 |
| Keyword | KW-0181--Complete proteome |
| Interpro | IPR003653--Peptidase_C48_C |
| PROSITE | PS50600--ULP_PROTEASE |
| Pfam | PF02902--Peptidase_C48 |
| Gene Ontology | GO:0005737--C:cytoplasm |