dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000455
Uniprot Accession O13559; YRF14_YEAST; D6VZ97;
Genbank Protein ID NP_013571.3;
Genbank Nucleotide ID NM_001182354.3;
Protein Name Y' element ATP-dependent helicase protein 1 copy 4
Protein Synonyms/Alias
Gene Name YRF1-4
Gene Synonyms/Alias YLR466W;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 Catalyzes DNA unwinding and is involved in telomerase-independent telomere maintenance.
Phosphorylation Sites
 dbPAF PTMs: 8
PositionPeptidesSourceReferences ( PMIDs )
801RLAEKQATASMSIIAcurated22817900
803AEKQATASMSIIALPcurated22817900
812SIIALPSSFQESNSSPhosphoGRID 2.0;curated19779198; 22817900
816LPSSFQESNSSDRCRcurated22817900
818SSFQESNSSDRCRKYcurated22817900
819SFQESNSSDRCRKYCPhosphoGRID 2.0;curated19779198; 22817900
859TNATTTASTNVRTSAcurated22817900
1015ESYKRKGSQMVLLERPhosphoGRID 2.0;curated19779198; 22817900
Sequence
(Fasta)		MWKTLGRVEQ LLPYASLILR NREVLFREPK RGIDEYLEND SFFQMIPVKY REIVLPKLRR 60
DTNKMTAALK NKVAVAIDEL TVPLMWMIHF AVGYPYRYPE LQLLAFAGPQ RNVYVDDTTR 120
RIQLYTDYNK NGSSEPRLKT LDGLTSDYVF YFVTVLRQMQ ICALGNSYDA FNHDPWMDVV 180
GFEDPDQVTN RDISRIVLYS YMFLNTAKGC LVEYATFRQY MRELPKNAPQ KLNFREMRQG 240
LIALGRHCVG SRFETDLYES ATSELMANHS VQTGRNIYGV DSFSLTSVSG TTATLLQERA 300
SERWIQWLGL ESDYHCSFSS TRNAEDVVAG EAASSDHHQK ISRVTRKRPR EPKSTNDILV 360
AGRKLFGSSF EFRDLHQLRL CHEIYMADTP SVAVQAPPGY GKTELFHLPL IALASKGDVK 420
YVSFLFVPYT VLLANCMIRL SRCGCLNVAP VRNFIEEGCD GVTDLYVGIY DDLASTNFTD 480
RIAAWENIVE CTFRTNNVKL GYLIVDEFHN FETEVYRQSQ FGGITNLDFD AFEKAIFLSG 540
TAPEAVADAA LQRIGLTGLA KKSMDINELK RSEDLSRGLS SYPTRMFNLI KEKSEVPLGH 600
VHKIWKKVES QPEEALKLLL ALFEIEPESK AIVVASTTNE VEELACSWRK YFRVVWIHGK 660
LGAAEKVSRT KEFVTDGSMR VLIGTKLVTE GIDIKQLMMV IMLDNRLNII ELIQGVGRLR 720
DGGLCYLLSR KNSWAARNRK GELPPIKEGC ITEQVREFYG LESKKGKKGQ HVGCCGSRTD 780
LSADTVELIE RMDRLAEKQA TASMSIIALP SSFQESNSSD RCRKYCSSDE DSDTCIHGSA 840
NASTNATTNS STNATTTAST NVRTSATTTA SINVRTSAIT TESTNSSTNA TTTASTNVRT 900
SATTTASINV RTSATTTEST NSNTSATTTE STDSNTSATT TESTDSNTSA TTTASTNSST 960
NATTTASTNS STNATTTEST NASAKEDANK DGNAEDNRFH PVTDINKESY KRKGSQMVLL 1020
ERKKLKAQFP NTSENMNVLQ FLGFRSDEIK HLFLYGIDVY FCPEGVFTQY GLCKGCQKMF 1080
ELCVCWAGQK VSYRRMAWEA LAVERMLRND EEYKEYLEDI EPYHGDPVGY LKYFSVKRGE 1140
IYSQIQRNYA WYLAITRRRE TISVLDSTRG KQGSQVFRMS GRQIKELYYK VWSNLRESKT 1200
EVLQYFLNWD EKKCREEWEA KDDTVFVEAL EKVGVFQRLR SMTSAGLQGP QYVKLQFSRH 1260
HRQLRSRYEL SLGMHLRDQL ALGVTPSKVP HWTAFLSMLI GLFYNKTFRQ KLEYLLEQIS 1320
EVWLLPHWLD LANVEVLAAD NTRVPLYMLM VAVHKELDSD DVPDGRFDII LLCRDSSREV 1380
GE 1383
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0347--Helicase
KW-0378--Hydrolase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0677--Repeat
Interpro

IPR011545--DEAD/DEAH_box_helicase_dom
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase
PROSITE

PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
Pfam

PF00270--DEAD
PF00271--Helicase_C
Gene Ontology

GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0003678--F:DNA helicase activity
GO:0003676--F:nucleic acid binding
GO:0032508--P:DNA duplex unwinding
GO:0000722--P:telomere maintenance via recombination