dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0000444
Uniprot Accession O13282; TAF5_SCHPO;
Genbank Protein ID NP_587902.1;
Genbank Nucleotide ID NM_001022894.2;
Protein Name Transcription initiation factor TFIID subunit 5
Protein Synonyms/Alias Transcription initiation factor TFIID 72 kDa subunit;TAFII-72;
Gene Name taf5
Gene Synonyms/Alias taf72;SPCC5E4.03c;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)
TAFs are components of the transcription factor IID (TFIID) complex that are essential for mediating regulation of RNA polymerase transcription. Regulates the genes involved in ubiquitin-dependent proteolysis during the progression of M-phase of mitosis.
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
256QNDPNNQSPKLLKEFdbPTM 3.0;UniProt;curated18257517; 16381945; 23193290; 22817900
Sequence
(Fasta)
MSATNGPQPQ DLNRIVLDYL AKKGYSRTEA MLRLEASGSG VSVEEKLKSI EETPDAYTHT 60
YTILRDWVDS SLELYKAELH RILFPIFVHS YLNLLSQDHY EAAKQFYELF KDDHTDLHDF 120
DVKNLKSLSL PSHVAEDRTA QQYRQNKYQL HFSRITFDLL LHFLFENVSN GGSIIIKLIN 180
QHIDIHIVPG RPTVLENAKV INEQEGITGQ SFERGDAQLQ PVKLQQMPMD KEMEKIVEMD 240
LEEEDMMHQN DPNNQSPKLL KEFRKLHEPN AEDAPSRDYI PLPPHKGVDI LSEVEAVKDW 300
SKRLHLGPRA SLPSVCMYTF HHTNNNMNCA EFSPDSTMIA CGFQESYIRL WSIKADKKSL 360
PKSTSVEDSD GSVRLLSHSG PVYGTTFSPD NKYLLSCSED ASARLWSVDT KTALVAYKGH 420
TGPVWDVAFG PFGHYFATAS HDQTAQLWSC DHIYPLRVFA GHLSDVDCVT FHPNSAYVLT 480
GSSDKTCRLW DVHRGHSVRV FNGHTQPVTA VAIAPDGHTM ASADSEGLIH LWDIGTGRRI 540
KTMRGHRGNI YSLSFSREST VLVSGGSDCT VRAWDVFKTN YNNPVSSSLT GSVVTPFSAK 600
TSTFNEVNWS TSPDQMVALY TKQTPIFNVS FTRRNLCLAI SVS 644
Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR006594--LisH
IPR007582--TFIID-su_WD40-assoc_reg
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50896--LISH
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08513--LisH
PF04494--TFIID_NTD2
PF00400--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0000124--C:SAGA complex
GO:0005669--C:transcription factor TFIID complex
GO:0006338--P:chromatin remodeling
GO:0016573--P:histone acetylation
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006367--P:transcription initiation from RNA polymerase II promoter