dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000441
Uniprot Accession O09174; AMACR_MOUSE; Q543Q9; Q9DCW6;
Genbank Protein ID NP_032563.2;
Genbank Nucleotide ID NM_008537.4;
Protein Name Alpha-methylacyl-CoA racemase
Protein Synonyms/Alias 2-methylacyl-CoA racemase;
Gene Name Amacr
Gene Synonyms/Alias Macr1;
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)		 Racemization of 2-methyl-branched fatty acid CoA esters. Responsible for the conversion of pristanoyl-CoA and C27-bile acyl-CoAs to their (S)-stereoisomers.
Phosphorylation Sites
 dbPAF PTMs: 6
PositionPeptidesSourceReferences ( PMIDs )
39VRVNRLGSTGENFLAdbPTM 3.0;PhosphoSitePlus;curated21183079; 16381945; 23193290; 22135298; 22817900
40RVNRLGSTGENFLARPhosphoSitePlus;curated22135298; 23984901
112RLSGFGQSGIFSKVAPhosphoSitePlus22135298
313QHNRERASFITDGEQPhosphoSitePlus22135298
323TDGEQLPSPRPAPLLPhosphoPep 2.0;PhosphoSitePlus;curated19060867; 22135298; 21743459; 21183079; 23984901; 25338131
344PSAKRDPSVGEHTVEPhosphoSitePlus22135298
Sequence
(Fasta)		MVLRGVRVVE LAGLAPGPFC GMVLADFGAE VVRVNRLGST GENFLARGKR SLALDLKRSQ 60
GVTVLRRMCA RADVLLEPFR CGVMEKLQLG PETLLQDNPK LIYARLSGFG QSGIFSKVAG 120
HDINYLALSG VLSKIGRSGE NPYPPLNLLA DFGGGGLMCT LGIVLALFER TRSGRGQVID 180
SSMVEGTAYL SSFLWKTQPM GLWKQPRGQN ILDGGAPFYT TYKTADGEFM AVGAIEPQFY 240
ALLLKGLGLE SEELPSQMSS ADWPEMKKKF ADVFAKKTKA EWCQIFDGTD ACVTPVLTFE 300
EALHHQHNRE RASFITDGEQ LPSPRPAPLL SRTPAVPSAK RDPSVGEHTV EVLREYGFSQ 360
EEILQLHSDR IVESDKLKAN L 382
Keyword

KW-0007--Acetylation
KW-0181--Complete proteome
KW-0903--Direct protein sequencing
KW-0413--Isomerase
KW-0496--Mitochondrion
KW-0576--Peroxisome
KW-1185--Reference proteome
Interpro

IPR003673--CoA-Trfase_fam_III
IPR023606--CoA-Trfase_III_dom
PROSITE
Pfam

PF02515--CoA_transf_3
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005739--C:mitochondrion
GO:0005777--C:peroxisome
GO:0008111--F:alpha-methylacyl-CoA racemase activity
GO:0005102--F:receptor binding
GO:0006699--P:bile acid biosynthetic process
GO:0008206--P:bile acid metabolic process
GO:0006631--P:fatty acid metabolic process
GO:0008300--P:isoprenoid catabolic process