dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000440
Uniprot Accession O09173; HGD_MOUSE; Q7TPP2;
Genbank Protein ID NP_038575.2;
Genbank Nucleotide ID NM_013547.3;
Protein Name Homogentisate 1,2-dioxygenase
Protein Synonyms/Alias Homogentisate oxygenase;Homogentisic acid oxidase;Homogentisicase;
Gene Name Hgd
Gene Synonyms/Alias Aku;Hgo;
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 8
PositionPeptidesSourceReferences ( PMIDs )
37NNPQVCPYNLYAEQLSysPTM 2.017242355; 19366988
40QVCPYNLYAEQLSGSPhosphoSitePlus;curated22135298; 25195567
69YRILPSVSHKPFESIcurated23567750
114EKKVDFVSGLYTLCGcurated23984901
117VDFVSGLYTLCGAGDPhosphoSitePlus;SysPTM 2.022135298; 17242355; 19366988
333DKTFRPPYYHRNCMSPhosphoSitePlus;SysPTM 2.0;curated22135298; 17242355; 19366988; 25195567
438RSHFTPNSRSPTEPKcurated21743459
440HFTPNSRSPTEPK--PhosphoSitePlus;curated22135298; 23984901
Sequence
(Fasta)		MAELKYISGF GNECASEDPR CPGSLPKGQN NPQVCPYNLY AEQLSGSAFT CPRNTNKRSW 60
LYRILPSVSH KPFESIDQGH VTHNWDEVGP DPNQLRWKPF EIPKASEKKV DFVSGLYTLC 120
GAGDIKSNNG LAVHIFLCNS SMENRCFYNS DGDFLIVPQK GKLLIYTEFG KMSLQPNEIC 180
VIQRGMRFSV DVFEETRGYI LEVYGVHFEL PDLGPIGANG LANPRDFLIP VAWYEDRRVP 240
GGYTVINKFQ GKLFACKQDV SPFNVVAWHG NYTPYKYNLE NFMVINAVAF DHADPSIFTV 300
LTAKSLRPGV AIADFVIFPP RWGVADKTFR PPYYHRNCMS EFMGLIKGHY EAKQGGFLPG 360
GGSLHSAMTP HGPDADCFEK ASKAKLEPER IADGTMAFMF ESSLSLAVTK WGLKTCSCLD 420
ENYYKCWEPL RSHFTPNSRS PTEPK 446
Keyword

KW-0007--Acetylation
KW-0181--Complete proteome
KW-0223--Dioxygenase
KW-0903--Direct protein sequencing
KW-0408--Iron
KW-0479--Metal-binding
KW-0560--Oxidoreductase
KW-0585--Phenylalanine catabolism
KW-1185--Reference proteome
KW-0828--Tyrosine catabolism
Interpro

IPR005708--Homogentis_dOase
IPR014710--RmlC-like_jellyroll
IPR011051--RmlC_Cupin
PROSITE
Pfam

PF04209--HgmA
Gene Ontology

GO:0070062--C:extracellular exosome
GO:0004411--F:homogentisate 1,2-dioxygenase activity
GO:0046872--F:metal ion binding
GO:0006520--P:cellular amino acid metabolic process
GO:0006559--P:L-phenylalanine catabolic process
GO:0006572--P:tyrosine catabolic process