| Tag |
Content |
| dbPAF ID |
dbPAF-0000433 |
| Uniprot Accession |
O09131; GSTO1_MOUSE; Q3TH87;
|
| Genbank Protein ID |
NP_034492.1;
|
| Genbank Nucleotide ID |
NM_010362.2;
|
| Protein Name |
Glutathione S-transferase omega-1 |
| Protein Synonyms/Alias |
|
| Gene Name |
Gsto1 |
| Gene Synonyms/Alias |
Gstx;Gtsttl; |
| Organism |
Mus musculus(Mouse) |
| NCBI Taxa ID |
10090 |
Functional Description
(View all) |
Exhibits glutathione-dependent thiol transferase and dehydroascorbate reductase activities. Has S-(phenacyl)glutathione reductase activity. Has also glutathione S-transferase activity. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA) and dimethylarsonic acid (By similarity).Functional Description
Exhibits glutathione-dependent thiol transferase and dehydroascorbate reductase activities. Has S-(phenacyl)glutathione reductase activity. Has also glutathione S-transferase activity. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA) and dimethylarsonic acid (By similarity). |
Phosphorylation Sites
|
dbPAF PTMs: 5 |
Sequence
(Fasta) | MSGESSRSLG KGSAPPGPVP EGQIRVYSMR FCPFAQRTLM VLKAKGIRHE VININLKNKP 60
EWFFEKNPLG LVPVLENSQG HLVTESVITC EYLDEAYPEK KLFPDDPYKK ARQKMTLESF 120
SKVPPLIASF VRSKRKEDSP NLREALENEF KKLEEGMDNY KSFLGGDSPS MVDYLTWPWF 180
QRLEALELKE CLAHTPKLKL WMAAMQQDPV ASSHKIDAKT YREYLNLYLQ DSPEACDYGL 240
241Fasta Sequence
>O09131|Gsto1|Mus musculus(Mouse)
MSGESSRSLGKGSAPPGPVPEGQIRVYSMRFCPFAQRTLMVLKAKGIRHEVININLKNKPEWFFEKNPLGLVPVLENSQGHLVTESVITCEYLDEAYPEKKLFPDDPYKKARQKMTLESFSKVPPLIASFVRSKRKEDSPNLREALENEFKKLEEGMDNYKSFLGGDSPSMVDYLTWPWFQRLEALELKECLAHTPKLKLWMAAMQQDPVASSHKIDAKTYREYLNLYLQDSPEACDYGL
|
| Keyword |
KW-0007--Acetylation
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0560--Oxidoreductase
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0808--Transferase
|
| Interpro |
IPR010987--Glutathione-S-Trfase_C-like
IPR004045--Glutathione_S-Trfase_N
IPR004046--GST_C
IPR005442--GST_omega
IPR012336--Thioredoxin-like_fold
|
| PROSITE |
PS50405--GST_CTER
PS50404--GST_NTER
|
| Pfam |
PF00043--GST_C
PF13417--GST_N_3
|
| Gene Ontology |
GO:0030424--C:axon
GO:0005604--C:basement membrane
GO:0044297--C:cell body
GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0043209--C:myelin sheath
GO:0031965--C:nuclear membrane
GO:0045174--F:glutathione dehydrogenase (ascorbate) activity
GO:0004364--F:glutathione transferase activity
GO:0050610--F:methylarsonate reductase activity
GO:0016491--F:oxidoreductase activity
GO:0071243--P:cellular response to arsenic-containing substance
GO:0006749--P:glutathione metabolic process
GO:0019853--P:L-ascorbic acid biosynthetic process
GO:0019852--P:L-ascorbic acid metabolic process
GO:0060315--P:negative regulation of ryanodine-sensitive calcium-release channel activity
GO:0055114--P:oxidation-reduction process
GO:0060316--P:positive regulation of ryanodine-sensitive calcium-release channel activity
GO:0010880--P:regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
GO:0042178--P:xenobiotic catabolic process
|
