| Tag |
Content |
| dbPAF ID |
dbPAF-0000421 |
| Uniprot Accession |
O09047; C3AR_MOUSE; O35951;
|
| Genbank Protein ID |
NP_033909.1;
|
| Genbank Nucleotide ID |
NM_009779.2;
|
| Protein Name |
C3a anaphylatoxin chemotactic receptor |
| Protein Synonyms/Alias |
|
| Gene Name |
C3ar1 |
| Gene Synonyms/Alias |
C3r1; |
| Organism |
Mus musculus(Mouse) |
| NCBI Taxa ID |
10090 |
Functional Description
(View all) |
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.Functional Description
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production. |
Phosphorylation Sites
|
dbPAF PTMs: 3 |
Sequence
(Fasta) | MESFDADTNS TDLHSRPLFQ PQDIASMVIL GLTCLLGLLG NGLVLWVAGV KMKTTVNTVW 60
FLHLTLADFL CCLSLPFSLA HLILQGHWPY GLFLCKLIPS IIILNMFASV FLLTAISLDR 120
CLIVHKPIWC QNHRNVRTAF AICGCVWVVA FVMCVPVFVY RDLFIMDNRS ICRYNFDSSR 180
SYDYWDYVYK LSLPESNSTD NSTAQLTGHM NDRSAPSSVQ ARDYFWTVTT ALQSQPFLTS 240
PEDSFSLDSA NQQPHYGGKP PNVLTAAVPS GFPVEDRKSN TLNADAFLSA HTELFPTASS 300
GHLYPYDFQG DYVDQFTYDN HVPTPLMAIT ITRLVVGFLV PFFIMVICYS LIVFRMRKTN 360
FTKSRNKTFR VAVAVVTVFF ICWTPYHLVG VLLLITDPES SLGEAVMSWD HMSIALASAN 420
SCFNPFLYAL LGKDFRKKAR QSIKGILEAA FSEELTHSTN CTQDKASSKR NNMSTDV
478Fasta Sequence
>O09047|C3ar1|Mus musculus(Mouse)
MESFDADTNSTDLHSRPLFQPQDIASMVILGLTCLLGLLGNGLVLWVAGVKMKTTVNTVWFLHLTLADFLCCLSLPFSLAHLILQGHWPYGLFLCKLIPSIIILNMFASVFLLTAISLDRCLIVHKPIWCQNHRNVRTAFAICGCVWVVAFVMCVPVFVYRDLFIMDNRSICRYNFDSSRSYDYWDYVYKLSLPESNSTDNSTAQLTGHMNDRSAPSSVQARDYFWTVTTALQSQPFLTSPEDSFSLDSANQQPHYGGKPPNVLTAAVPSGFPVEDRKSNTLNADAFLSAHTELFPTASSGHLYPYDFQGDYVDQFTYDNHVPTPLMAITITRLVVGFLVPFFIMVICYSLIVFRMRKTNFTKSRNKTFRVAVAVVTVFFICWTPYHLVGVLLLITDPESSLGEAVMSWDHMSIALASANSCFNPFLYALLGKDFRKKARQSIKGILEAAFSEELTHSTNCTQDKASSKRNNMSTDV
|
| Keyword |
KW-1003--Cell membrane
KW-0145--Chemotaxis
KW-0181--Complete proteome
KW-1015--Disulfide bond
KW-0297--G-protein coupled receptor
KW-0325--Glycoprotein
KW-0472--Membrane
KW-0597--Phosphoprotein
KW-0675--Receptor
KW-1185--Reference proteome
KW-0765--Sulfation
KW-0807--Transducer
KW-0812--Transmembrane
KW-1133--Transmembrane helix
|
| Interpro |
IPR001644--Anaphtx_C3AR1
IPR002234--Anphylx_rcpt
IPR000826--Formyl_rcpt-rel
IPR000276--GPCR_Rhodpsn
IPR017452--GPCR_Rhodpsn_7TM
|
| PROSITE |
PS00237--G_PROTEIN_RECEP_F1_1
PS50262--G_PROTEIN_RECEP_F1_2
|
| Pfam |
PF00001--7tm_1
|
| Gene Ontology |
GO:0005829--C:cytosol
GO:0016021--C:integral component of membrane
GO:0005886--C:plasma membrane
GO:0004943--F:C3a anaphylatoxin receptor activity
GO:0004930--F:G-protein coupled receptor activity
GO:0006935--P:chemotaxis
GO:0002430--P:complement receptor mediated signaling pathway
GO:0045766--P:positive regulation of angiogenesis
GO:0007204--P:positive regulation of cytosolic calcium ion concentration
GO:2000573--P:positive regulation of DNA biosynthetic process
GO:0072126--P:positive regulation of glomerular mesangial cell proliferation
GO:0010759--P:positive regulation of macrophage chemotaxis
GO:0090023--P:positive regulation of neutrophil chemotaxis
GO:0048661--P:positive regulation of smooth muscle cell proliferation
GO:0010575--P:positive regulation of vascular endothelial growth factor production
GO:0008217--P:regulation of blood pressure
GO:0002462--P:tolerance induction to nonself antigen
|
