dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0000420
Uniprot Accession O09044; SNP23_MOUSE; O35620;
Genbank Protein ID NP_001171263.1; NP_001171264.1; NP_033248.1; XP_006499120.1;
Genbank Nucleotide ID NM_001177792.1; NM_001177793.1; NM_009222.3; XM_006499057.2;
Protein Name Synaptosomal-associated protein 23
Protein Synonyms/Alias
Gene Name Snap23
Gene Synonyms/Alias Sndt;
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion.
Phosphorylation Sites
dbPAF PTMs: 15
PositionPeptidesSourceReferences ( PMIDs )
5---MDNLSPEEVQLRdbPTM 3.0;PHOSIDA;PhosphoSitePlus;curated19854140; 16381945; 23193290; 21081558; 22135298; 25338131
17QLRAHQVTDESLESTPHOSIDA21081558
20AHQVTDESLESTRRIdbPTM 3.0;Phospho.ELM 9.0;PHOSIDA;PhosphoSitePlus;SysPTM 2.0;UniProt;curated19144319; 16381945; 23193290; 19367708; 18846507; 21081558;
23VTDESLESTRRILGLdbPTM 3.0;Phospho.ELM 9.0;PHOSIDA;PhosphoSitePlus;SysPTM 2.0;UniProt;curated18846507; 16381945; 23193290; 19144319; 21081558; 22135298;
34ILGLAIESQDAGIKTdbPTM 3.0;Phospho.ELM 9.0;PhosphoSitePlus;UniProt;curated19144319; 16381945; 23193290; 22135298; 25338131
95NRTKNFESGKNYKATdbPTM 3.0;PhosphoSitePlus18692471; 16381945; 23193290; 22135298
102SGKNYKATWGDGGDNPhosphoSitePlus22135298
110WGDGGDNSPSNVVSKdbPTM 3.0;Phospho.ELM 9.0;PHOSIDA;PhosphoPep 2.0;PhosphoSitePlus;SysPTM 2.0;UniProt;curated17242355; 18630941; 19144319; 16381945; 23193290; 14729942;
112DGGDNSPSNVVSKQPdbPTM 3.0;PHOSIDA;PhosphoPep 2.0;PhosphoSitePlus;curated14729942; 16381945; 23193290; 21081558; 19060867; 22135298;
116NSPSNVVSKQPSRITPHOSIDA;PhosphoSitePlus;curated21081558; 22135298; 25338131
120NVVSKQPSRITNGQPdbPTM 3.0;Phospho.ELM 9.0;PHOSIDA;PhosphoSitePlus;curated18692471; 20531401; 16381945; 23193290; 19144319; 21081558;
123SKQPSRITNGQPQQTPHOSIDA;curated21081558; 24704852; 25338131
138TGAASGGYIKRITNDPhosphoSitePlus22135298
156DEMEENLTQVGSILGPhosphoSitePlus22135298
160ENLTQVGSILGNLKNdbPTM 3.0;Phospho.ELM 9.0;PhosphoPep 2.0;PhosphoSitePlus;UniProt;curated21183079; 16381945; 23193290; 19144319; 19060867; 22135298;
Sequence
(Fasta)
MDNLSPEEVQ LRAHQVTDES LESTRRILGL AIESQDAGIK TITMLDEQGE QLNRIEEGMD 60
QINKDMREAE KTLTELNKCC GLCICPCNRT KNFESGKNYK ATWGDGGDNS PSNVVSKQPS 120
RITNGQPQQT TGAASGGYIK RITNDAREDE MEENLTQVGS ILGNLKNMAL DMGNEIDAQN 180
QQIQKITEKA DTNKNRIDIA NTRAKKLIDS 211
Keyword

KW-0007--Acetylation
KW-0965--Cell junction
KW-1003--Cell membrane
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0449--Lipoprotein
KW-0472--Membrane
KW-0564--Palmitate
KW-0597--Phosphoprotein
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0770--Synapse
KW-0771--Synaptosome
KW-0813--Transport

Interpro

IPR000928--SNAP-25
IPR000727--T_SNARE_dom

PROSITE

PS50192--T_SNARE

Pfam

PF00835--SNAP-25

Gene Ontology

GO:0042582--C:azurophil granule
GO:0005737--C:cytoplasm
GO:0031410--C:cytoplasmic vesicle
GO:0070062--C:extracellular exosome
GO:0005925--C:focal adhesion
GO:0042629--C:mast cell granule
GO:0043005--C:neuron projection
GO:0005654--C:nucleoplasm
GO:0005886--C:plasma membrane
GO:0031201--C:SNARE complex
GO:0042581--C:specific granule
GO:0045202--C:synapse
GO:0005484--F:SNAP receptor activity
GO:0019905--F:syntaxin binding
GO:0006887--P:exocytosis
GO:0002553--P:histamine secretion by mast cell
GO:0015031--P:protein transport
GO:0031629--P:synaptic vesicle fusion to presynaptic membrane
GO:0016082--P:synaptic vesicle priming