| Tag |
Content |
| dbPAF ID |
dbPAF-0000417 |
| Uniprot Accession |
O09032; ELAV4_RAT;
|
| Genbank Protein ID |
|
| Genbank Nucleotide ID |
|
| Protein Name |
ELAV-like protein 4 |
| Protein Synonyms/Alias |
Hu-antigen D;HuD;Paraneoplastic encephalomyelitis antigen HuD; |
| Gene Name |
Elavl4 |
| Gene Synonyms/Alias |
Hud; |
| Organism |
Rattus norvegicus(Rat) |
| NCBI Taxa ID |
10116 |
Functional Description
(View all) |
Binds to AU-rich sequences (AREs) of target mRNAs, including VEGF and FOS mRNA (By similarity). May play a role in neuron-specific RNA processing. Protects CDKN1A mRNA from decay by binding to its 3'-UTR.Functional Description
Binds to AU-rich sequences (AREs) of target mRNAs, including VEGF and FOS mRNA (By similarity). May play a role in neuron-specific RNA processing. Protects CDKN1A mRNA from decay by binding to its 3'-UTR. |
Phosphorylation Sites
|
dbPAF PTMs: 2 |
Sequence
(Fasta) | MEPQVSNGPT SNTSNGPSSN NRNCPSPMQT GAATDDSKTN LIVNYLPQNM TQEEFRSLFG 60
SIGEIESCKL VRDKITGQSL GYGFVNYIDP KDAEKAINTL NGLRLQTKTI KVSYARPSSA 120
SIRDANLYVS GLPKTMTQKE LEQLFSQYGR IITSRILVDQ VTGVSRGVGF IRFDKRIEAE 180
EAIKGLNGQK PSGATEPITV KFANNPSQKS SQALLSQLYQ SPNRRYPGPL HHQAQRFRLD 240
NLLNMAYGVK RLMSGPVPPS ACPPRFSPIT IDGMTSLVGM NIPGHTGTGW CIFVYNLSPD 300
SDESVLWQLF GPFGAVNNVK VIRDFNTNKC KGFGFVTMTN YDEAAMAIAS LNGYRLGDRV 360
LQVSFKTNKA HKS
374Fasta Sequence
>O09032|Elavl4|Rattus norvegicus(Rat)
MEPQVSNGPTSNTSNGPSSNNRNCPSPMQTGAATDDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRLMSGPVPPSACPPRFSPITIDGMTSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKAHKS
|
| Keyword |
KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0488--Methylation
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0694--RNA-binding
|
| Interpro |
IPR006548--ELAD_HUD_SF
IPR002343--Hud_Sxl_RNA
IPR012677--Nucleotide-bd_a/b_plait
IPR000504--RRM_dom
|
| PROSITE |
PS50102--RRM
|
| Pfam |
PF00076--RRM_1
|
| Gene Ontology |
GO:0005737--C:cytoplasm
GO:0005856--C:cytoskeleton
GO:0005829--C:cytosol
GO:0030425--C:dendrite
GO:0030426--C:growth cone
GO:0016020--C:membrane
GO:0043025--C:neuronal cell body
GO:0005635--C:nuclear envelope
GO:0005634--C:nucleus
GO:0042788--C:polysomal ribosome
GO:0017091--F:AU-rich element binding
GO:0003730--F:mRNA 3'-UTR binding
GO:0003729--F:mRNA binding
GO:0000166--F:nucleotide binding
GO:0007568--P:aging
GO:0008306--P:associative learning
GO:1990090--P:cellular response to nerve growth factor stimulus
GO:0048813--P:dendrite morphogenesis
GO:0007626--P:locomotory behavior
GO:0007399--P:nervous system development
GO:0030182--P:neuron differentiation
GO:1900006--P:positive regulation of dendrite development
GO:0031099--P:regeneration
GO:0043488--P:regulation of mRNA stability
GO:0042220--P:response to cocaine
GO:0034976--P:response to endoplasmic reticulum stress
|
