dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0000416
Uniprot Accession O09030; I13R1_MOUSE; Q7TT27;
Genbank Protein ID NP_598751.3;
Genbank Nucleotide ID NM_133990.5;
Protein Name Interleukin-13 receptor subunit alpha-1
Protein Synonyms/Alias
Gene Name Il13ra1
Gene Synonyms/Alias Il13r;Il13ra;
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Binds with low affinity to interleukin-13 (IL13). Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity (By similarity).
Phosphorylation Sites
dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
402HWKKYDIYEKQSKEEdbPTM 3.0;Phospho.ELM 9.0;PhosphoSitePlus;curated10409622; 16381945; 23193290; 22135298; 22817900
412QSKEETDSVVLIENLcurated25338131
Sequence
(Fasta)
MARPALLGEL LVLLLWTATV GQVAAATEVQ PPVTNLSVSV ENLCTIIWTW SPPEGASPNC 60
TLRYFSHFDD QQDKKIAPET HRKEELPLDE KICLQVGSQC SANESEKPSP LVKKCISPPE 120
GDPESAVTEL KCIWHNLSYM KCSWLPGRNT SPDTHYTLYY WYSSLEKSRQ CENIYREGQH 180
IACSFKLTKV EPSFEHQNVQ IMVKDNAGKI RPSCKIVSLT SYVKPDPPHI KHLLLKNGAL 240
LVQWKNPQNF RSRCLTYEVE VNNTQTDRHN ILEVEEDKCQ NSESDRNMEG TSCFQLPGVL 300
ADAVYTVRVR VKTNKLCFDD NKLWSDWSEA QSIGKEQNST FYTTMLLTIP VFVAVAVIIL 360
LFYLKRLKII IFPPIPDPGK IFKEMFGDQN DDTLHWKKYD IYEKQSKEET DSVVLIENLK 420
KAAP 425
Keyword

KW-0181--Complete proteome
KW-1015--Disulfide bond
KW-0325--Glycoprotein
KW-0472--Membrane
KW-0675--Receptor
KW-1185--Reference proteome
KW-0677--Repeat
KW-0732--Signal
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR003961--FN3_dom
IPR013783--Ig-like_fold
IPR003532--Short_hematopoietin_rcpt_2_CS
IPR015321--TypeI_recpt_CBD

PROSITE

PS50853--FN3
PS01356--HEMATOPO_REC_S_F2

Pfam

PF09240--IL6Ra-bind

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0004896--F:cytokine receptor activity