| Tag |
Content |
| dbPAF ID |
dbPAF-0000406 |
| Uniprot Accession |
O08984; LBR_RAT;
|
| Genbank Protein ID |
NP_604448.1;
|
| Genbank Nucleotide ID |
NM_134453.1;
|
| Protein Name |
Lamin-B receptor |
| Protein Synonyms/Alias |
Integral nuclear envelope inner membrane protein;NBP60; |
| Gene Name |
Lbr |
| Gene Synonyms/Alias |
|
| Organism |
Rattus norvegicus(Rat) |
| NCBI Taxa ID |
10116 |
Functional Description
(View all) |
Anchors the lamina and the heterochromatin to the inner nuclear membrane.Functional Description
Anchors the lamina and the heterochromatin to the inner nuclear membrane. |
Phosphorylation Sites
|
dbPAF PTMs: 4 |
Sequence
(Fasta) | MPGRKFADGE VVRGRWPGSS LYYEVEILSH DSTSQLYTVK YKDGTELELK ESDIKPLKSF 60
KQRKSGSTSS SPSRRRSSRS RSRSRSRSPG RAPKGSRRSV SASYQADAKE KEMRREILQV 120
KLTPLVLKPF ANSVSVYNGE PEHMEKSATP PKNKQERVIL STEDSYIATQ YSLRPRREEV 180
KPKHRVRGTN LVTRGPVPLG TFQVTTPQRR DLEFGGVPGA LLIMLGLPAC VFLLLLQCAQ 240
KDPGLLQFPP PLPALRELWE ARVCGVYLLW FFLQALFSLL PVGKVVEGTP LVDGRRLKYR 300
LNGLYAFILT SAAVGTAVFW DIELYYLYTH FLQFALAAIV FSVVLSVYLY ARSLKVPRDE 360
LSPASSGNAV YDFFIGRELN PRIGAFDLKF FCELRPGLIG WVVINLVMLL AEMKVQERSA 420
PSLAMTLVNS FQLLYVVDAL WFEEALLTTM DIIHDGFGFM LAFGDLVWVP FTYSLQAFYL 480
VNHPQDLSWP LTSVIIALKL CGYVIFRCAN SQKNAFRKNP TDPKLAHLKT IPTSTWKSLL 540
VSGWWGFVRH PNYLGDLIMA LAWSLPCGFN HILPYFYVIY FTALLIHREA RDEHQCRRKY 600
GLAWEKYCQR VPYRIFPYIY
621Fasta Sequence
>O08984|Lbr|Rattus norvegicus(Rat)
MPGRKFADGEVVRGRWPGSSLYYEVEILSHDSTSQLYTVKYKDGTELELKESDIKPLKSFKQRKSGSTSSSPSRRRSSRSRSRSRSRSPGRAPKGSRRSVSASYQADAKEKEMRREILQVKLTPLVLKPFANSVSVYNGEPEHMEKSATPPKNKQERVILSTEDSYIATQYSLRPRREEVKPKHRVRGTNLVTRGPVPLGTFQVTTPQRRDLEFGGVPGALLIMLGLPACVFLLLLQCAQKDPGLLQFPPPLPALRELWEARVCGVYLLWFFLQALFSLLPVGKVVEGTPLVDGRRLKYRLNGLYAFILTSAAVGTAVFWDIELYYLYTHFLQFALAAIVFSVVLSVYLYARSLKVPRDELSPASSGNAVYDFFIGRELNPRIGAFDLKFFCELRPGLIGWVVINLVMLLAEMKVQERSAPSLAMTLVNSFQLLYVVDALWFEEALLTTMDIIHDGFGFMLAFGDLVWVPFTYSLQAFYLVNHPQDLSWPLTSVIIALKLCGYVIFRCANSQKNAFRKNPTDPKLAHLKTIPTSTWKSLLVSGWWGFVRHPNYLGDLIMALAWSLPCGFNHILPYFYVIYFTALLIHREARDEHQCRRKYGLAWEKYCQRVPYRIFPYIY
|
| Keyword |
KW-0007--Acetylation
KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0325--Glycoprotein
KW-0472--Membrane
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-0675--Receptor
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
|
| Interpro |
IPR001171--Ergosterol_biosynth_ERG4_ERG24
IPR019023--Lamin-B_rcpt_of_tudor
IPR018083--Sterol_reductase_CS
IPR002999--Tudor
|
| PROSITE |
PS01017--STEROL_REDUCT_1
PS01018--STEROL_REDUCT_2
|
| Pfam |
PF01222--ERG4_ERG24
PF09465--LBR_tudor
|
| Gene Ontology |
GO:0005737--C:cytoplasm
GO:0005639--C:integral component of nuclear inner membrane
GO:0005643--C:nuclear pore
GO:0051087--F:chaperone binding
GO:0003677--F:DNA binding
GO:0008139--F:nuclear localization sequence binding
GO:0016627--F:oxidoreductase activity, acting on the CH-CH group of donors
GO:0016628--F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
GO:0006695--P:cholesterol biosynthetic process
GO:0007067--P:mitotic nuclear division
GO:0006998--P:nuclear envelope organization
|
