dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000405
Uniprot Accession O08983; HPS1_MOUSE; O35155; O35725; O35950;
Genbank Protein ID NP_062297.1;
Genbank Nucleotide ID NM_019424.2;
Protein Name Hermansky-Pudlak syndrome 1 protein homolog
Protein Synonyms/Alias
Gene Name Hps1
Gene Synonyms/Alias Ep;Hps;
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)		 Component of multiple cytoplasmic organelles. Apparently crucial for their normal development and function. May be involved in intracellular protein sorting.
Phosphorylation Sites
 dbPAF PTMs: 7
PositionPeptidesSourceReferences ( PMIDs )
269SPQRRPKSSQNIPVQcurated25266776; 23684622; 25338131
270PQRRPKSSQNIPVQQcurated25266776
282VQQARSQSTSVPTRSPhosphoSitePlus;curated22135298; 25266776; 23684622
284QARSQSTSVPTRSSRPhosphoSitePlus;curated22135298; 23684622
287SQSTSVPTRSSRETDcurated23684622
289STSVPTRSSRETDTDcurated23684622
290TSVPTRSSRETDTDScurated23684622
Sequence
(Fasta)		MKCVLVATEG AEVLFYWTDE EFAESLRLKL QQSEDEEEEL PVLEDQLSTL LAPVIISSMT 60
MLEKLSDTYT CFSTENDNHL YVLHLFGEYL FVAINGDHSE SEGDLRRKLC VLKYLFEVHF 120
GLVTVDGQLI RKELRPPDLE ERARVWKHFQ RLLGTYSYLR DREQSFAVEA VERLIHPQLC 180
EQSIETLERH VVQAINASPE RGGEEVLHAF LLVHCKLLAF YSGHGASTLR PADLLALILL 240
VQDLQPSPGT TEEEEEEEDS DSPQRRPKSS QNIPVQQARS QSTSVPTRSS RETDTDSISL 300
PEEYFTPAPS PGDQSSGSLV WLDGGTPPSD ALQMAEDTPE GLASHSPELP SPRRIFLDAN 360
IKENYCPLVP HTMYCLPLWP GINMVLLTKS PSTPLALILY QLLDGFSLLE KKLKEGQEAG 420
SALRSQPFVA DLRQKMDKFI KNRVGQEIQN TWLEFKSKAF SRSEPGSSWE LLQVCGKLKR 480
QLCVIYRLSF LVTAPSRGGP HLPQHLQDRA QKLMKERLLD WKDFLLVKSR RNVTMVSYLE 540
DFPGLVHFIY VDRTTGQMVA PSLSPNEKMS SELGKGPLAA FVKAKVWALV RLARRYLQKG 600
CTTLLFQEGD FRCSYFLWFE NDMGYKLQMI EVPVLSDDSV PIGVLGGDYY RKLLRYYSKS 660
HPSEPVRCYE LLTLHLSVIP TDLLVQQASQ LARRLGEASR VTLP 705
Keyword

KW-0015--Albinism
KW-0181--Complete proteome
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0677--Repeat
Interpro

IPR026053--HPS1
PROSITE
Pfam
Gene Ontology

GO:0031085--C:BLOC-3 complex
GO:0016023--C:cytoplasmic membrane-bounded vesicle
GO:0046983--F:protein dimerization activity
GO:0007596--P:blood coagulation
GO:0048069--P:eye pigmentation
GO:0030318--P:melanocyte differentiation
GO:0006996--P:organelle organization
GO:0043473--P:pigmentation
GO:0032816--P:positive regulation of natural killer cell activation
GO:0060041--P:retina development in camera-type eye
GO:0033299--P:secretion of lysosomal enzymes