dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000400
Uniprot Accession O08949; TF2AA_RAT;
Genbank Protein ID NP_071544.1;
Genbank Nucleotide ID NM_022208.1;
Protein Name Transcription initiation factor IIA subunit 1
Protein Synonyms/Alias General transcription factor IIA subunit 1;
Gene Name Gtf2a1
Gene Synonyms/Alias
Organism Rattus norvegicus(Rat)
NCBI Taxa ID 10116
Functional Description
(View all)		 TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity (By similarity).
Phosphorylation Sites
 dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
317VEEEPLNSEDDVSDEPhosphoSitePlus;UniProt22135298; 22673903
322LNSEDDVSDEEGQELPhosphoSitePlus;UniProt22135298; 22673903
Sequence
(Fasta)		MANSANTNTV PKLYRSVIED VINDVRDIFL DDGVDEQVLM ELKTLWENKL MQSRAVDGFH 60
SEEQQLLLQV QQQHQPQQQQ HHHHHHHQQA QPQQTVPQQA QTQQVLIPAS QQATAPQVIV 120
PDSKLIQHMN ASSITSAAAT AATLALPAGV TPVQQILTNS GQLLQVVRAA NGAQYIFQPQ 180
QSVVLQQQVI PQMQPGGVQA PVIQQVLAPL PGGISPQTGV IIQPQQILFT GNKTQVIPTT 240
VAAPTPAQAQ IPAAGQQQPQ AQPAQQQAPL VLQVDGTGDT SSEEDEDEEE DYDDDEEEDK 300
EKDGAEDGQV EEEPLNSEDD VSDEEGQELF DTENVVVCQY DKIHRSKNKW KFHLKDGIMN 360
LNGRDYIFSK AIGDAEW 378
Keyword

KW-0007--Acetylation
KW-0181--Complete proteome
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
Interpro

IPR009083--TFIIA_a-hlx
IPR004855--TFIIA_asu/bsu
IPR013028--TFIIA_asu_N
IPR009088--TFIIA_b-brl
PROSITE
Pfam

PF03153--TFIIA
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005672--C:transcription factor TFIIA complex
GO:0003677--F:DNA binding
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006366--P:transcription from RNA polymerase II promoter
GO:0006367--P:transcription initiation from RNA polymerase II promoter