| Tag |
Content |
| dbPAF ID |
dbPAF-0000397 |
| Uniprot Accession |
O08917; FLOT1_MOUSE;
|
| Genbank Protein ID |
NP_032053.1; XP_006523719.1; XP_006536579.1; XP_006537312.1;
|
| Genbank Nucleotide ID |
NM_008027.2; XM_006523656.2; XM_006536516.2; XM_006537249.2;
|
| Protein Name |
Flotillin-1 |
| Protein Synonyms/Alias |
|
| Gene Name |
Flot1 |
| Gene Synonyms/Alias |
|
| Organism |
Mus musculus(Mouse) |
| NCBI Taxa ID |
10090 |
Functional Description
(View all) |
May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles.Functional Description
May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. |
Phosphorylation Sites
|
dbPAF PTMs: 4 |
Sequence
(Fasta) | MFFTCGPNEA MVVSGFCRSP PVMVAGGRVF VLPCIQQIQR ISLNTLTLNV KSEKVYTRHG 60
VPISVTGIAQ VKIQGQNKEM LAAACQMFLG KTEAEIAHIA LETLEGHQRA IMAHMTVEEI 120
YKDRQKFSEQ VFKVASSDLV NMGISVVSYT LKDIHDDQDY LHSLGKARTA QVQKDARIGE 180
AEAKRDAGIR EAKAKQEKVS AQCLSEIEMA KAQRDYELKK ATYDIEVNTR RAQADLAYQL 240
QVAKTKQQIE EQRVQVQVVE RAQQVAVQEQ EIARREKELE ARVRKPAEAE RYRLERLAEA 300
EKAQLIMQAE AEAESVRMRG EAEAFAIGAR ARAEAEQMAK KAEAFQMYQE AAQLDMLLEK 360
LPQVAEEISG PLTSANKITL VSSGSGTMGA AKVTGEVLDI LSRLPESVER LTGVSISQVN 420
HNKPLRTA
429Fasta Sequence
>O08917|Flot1|Mus musculus(Mouse)
MFFTCGPNEAMVVSGFCRSPPVMVAGGRVFVLPCIQQIQRISLNTLTLNVKSEKVYTRHGVPISVTGIAQVKIQGQNKEMLAAACQMFLGKTEAEIAHIALETLEGHQRAIMAHMTVEEIYKDRQKFSEQVFKVASSDLVNMGISVVSYTLKDIHDDQDYLHSLGKARTAQVQKDARIGEAEAKRDAGIREAKAKQEKVSAQCLSEIEMAKAQRDYELKKATYDIEVNTRRAQADLAYQLQVAKTKQQIEEQRVQVQVVERAQQVAVQEQEIARREKELEARVRKPAEAERYRLERLAEAEKAQLIMQAEAEAESVRMRGEAEAFAIGARARAEAEQMAKKAEAFQMYQEAAQLDMLLEKLPQVAEEISGPLTSANKITLVSSGSGTMGAAKVTGEVLDILSRLPESVERLTGVSISQVNHNKPLRTA
|
| Keyword |
KW-1003--Cell membrane
KW-0181--Complete proteome
KW-0903--Direct protein sequencing
KW-0967--Endosome
KW-0472--Membrane
KW-0597--Phosphoprotein
KW-1185--Reference proteome
|
| Interpro |
IPR001107--Band_7
IPR031905--Flotillin_C
IPR027705--Flotillin_fam
|
| PROSITE |
|
| Pfam |
PF01145--Band_7
PF15975--Flot
|
| Gene Ontology |
GO:0016323--C:basolateral plasma membrane
GO:0005901--C:caveola
GO:0005913--C:cell-cell adherens junction
GO:0044291--C:cell-cell contact zone
GO:0034451--C:centriolar satellite
GO:0008180--C:COP9 signalosome
GO:0030864--C:cortical actin cytoskeleton
GO:0031410--C:cytoplasmic vesicle
GO:0005769--C:early endosome
GO:0005768--C:endosome
GO:0070062--C:extracellular exosome
GO:0016600--C:flotillin complex
GO:0005925--C:focal adhesion
GO:0030027--C:lamellipodium
GO:0005765--C:lysosomal membrane
GO:0042470--C:melanosome
GO:0016020--C:membrane
GO:0045121--C:membrane raft
GO:0005815--C:microtubule organizing center
GO:0005886--C:plasma membrane
GO:0044853--C:plasma membrane raft
GO:0042383--C:sarcolemma
GO:0001931--C:uropod
GO:0002020--F:protease binding
GO:0046982--F:protein heterodimerization activity
GO:0007411--P:axon guidance
GO:0007409--P:axonogenesis
GO:0071360--P:cellular response to exogenous dsRNA
GO:0033227--P:dsRNA transport
GO:0006897--P:endocytosis
GO:0090002--P:establishment of protein localization to plasma membrane
GO:0022617--P:extracellular matrix disassembly
GO:0001765--P:membrane raft assembly
GO:0044854--P:plasma membrane raft assembly
GO:0060355--P:positive regulation of cell adhesion molecule production
GO:1901890--P:positive regulation of cell junction assembly
GO:2000049--P:positive regulation of cell-cell adhesion mediated by cadherin
GO:0001819--P:positive regulation of cytokine production
GO:0045807--P:positive regulation of endocytosis
GO:0034116--P:positive regulation of heterotypic cell-cell adhesion
GO:0032728--P:positive regulation of interferon-beta production
GO:1901741--P:positive regulation of myoblast fusion
GO:0032092--P:positive regulation of protein binding
GO:0001934--P:positive regulation of protein phosphorylation
GO:0048643--P:positive regulation of skeletal muscle tissue development
GO:0032226--P:positive regulation of synaptic transmission, dopaminergic
GO:0034141--P:positive regulation of toll-like receptor 3 signaling pathway
GO:0051260--P:protein homooligomerization
GO:0070528--P:protein kinase C signaling
GO:1903044--P:protein localization to membrane raft
GO:0072659--P:protein localization to plasma membrane
GO:0002090--P:regulation of receptor internalization
GO:0035023--P:regulation of Rho protein signal transduction
GO:0034976--P:response to endoplasmic reticulum stress
|
