dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0000395
Uniprot Accession O08912; GALT1_MOUSE; Q5BKS3; Q7TND1;
Genbank Protein ID NP_001153876.1; NP_038842.3; XP_006525713.1;
Genbank Nucleotide ID NM_001160404.1; NM_013814.3; XM_006525650.1;
Protein Name Polypeptide N-acetylgalactosaminyltransferase 1
Protein Synonyms/Alias Polypeptide GalNAc transferase 1;GalNAc-T1;pp-GaNTase 1;Protein-UDP acetylgalactosaminyltransferase 1;UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 1;
Gene Name Galnt1
Gene Synonyms/Alias
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has a broad spectrum of substrates for peptides such as EA2, Muc5AC, Muc1a, Muc1b and Muc7.
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
143VHSVINRSPRHMIEEPhosphoSitePlus22135298
Sequence
(Fasta)
MRKFAYCKVV LATSLVWVLL DMFLLLYFSE CNKCEEKQER GLPAGDVLEL VQKPHEGPGE 60
MGKPVVIPKE DQEKMKEMFK INQFNLMASE MIALNRSLPD VRLEGCKTKV YPDNLPTTSV 120
VIVFHNEAWS TLLRTVHSVI NRSPRHMIEE IVLVDDASER DFLKRPLESY VKKLKVPVHV 180
IRMEQRSGLI RARLKGAAVS RGQVITFLDA HCECTAGWLE PLLARIKHDR RTVVCPIIDV 240
ISDDTFEYMA GSDMTYGGFN WKLNFRWYPV PQREMDRRKG DRTLPVRTPT MAGGLFSIDR 300
DYFQEIGTYD AGMDIWGGEN LEISFRIWQC GGTLEIVTCS HVGHVFRKAT PYTFPGGTGQ 360
IINKNNRRLA EVWMDEFKNF FYIISPGVTK VDYGDISSRL GLRRKLQCKP FSWYLENIYP 420
DSQIPRHYFS LGEIRNVETN QCLDNMARKE NEKVGIFNCH GMGGNQVFSY TANKEIRTDD 480
LCLDVSKLNG PVTMLKCHHL KGNQLWEYDP VKLTLQHVNS NQCLDKATEE DSQVPSIRDC 540
TGSRSQQWLL RNVTLPEIF
Keyword

KW-0002--3D-structure
KW-0181--Complete proteome
KW-1015--Disulfide bond
KW-0325--Glycoprotein
KW-0328--Glycosyltransferase
KW-0333--Golgi apparatus
KW-0430--Lectin
KW-0464--Manganese
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0964--Secreted
KW-0735--Signal-anchor
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001173--Glyco_trans_2-like
IPR029044--Nucleotide-diphossugar_trans
IPR000772--Ricin_B_lectin

PROSITE

PS50231--RICIN_B_LECTIN

Pfam

PF00535--Glycos_transf_2
PF00652--Ricin_B_lectin

Gene Ontology

GO:0005576--C:extracellular region
GO:0032580--C:Golgi cisterna membrane
GO:0016021--C:integral component of membrane
GO:0016020--C:membrane
GO:0048471--C:perinuclear region of cytoplasm
GO:0030246--F:carbohydrate binding
GO:0030145--F:manganese ion binding
GO:0004653--F:polypeptide N-acetylgalactosaminyltransferase activity
GO:0006493--P:protein O-linked glycosylation
GO:0018242--P:protein O-linked glycosylation via serine
GO:0018243--P:protein O-linked glycosylation via threonine