dbPAF Protein Information
Tag | Content | ||||||||
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dbPAF ID | dbPAF-0000390 | ||||||||
Uniprot Accession | O08899; RGS4_MOUSE; Q99L30; | ||||||||
Genbank Protein ID | NP_033088.2; | ||||||||
Genbank Nucleotide ID | NM_009062.3; | ||||||||
Protein Name | Regulator of G-protein signaling 4 | ||||||||
Protein Synonyms/Alias | |||||||||
Gene Name | Rgs4 | ||||||||
Gene Synonyms/Alias | |||||||||
Organism | Mus musculus(Mouse) | ||||||||
NCBI Taxa ID | 10090 | ||||||||
Functional Description (View all) |
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on G(z)-alpha is inhibited by phosphorylation of the G-protein. Activity on G(z)-alpha and G(i)-alpha-1 is inhibited by palmitoylation of the G-protein (By similarity). | ||||||||
Phosphorylation Sites |
dbPAF PTMs: 1
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Sequence (Fasta) | MCKGLAGLPA SCLRSAKDMK HRLGFLLQKS DSCEHSSSHS KKDKVVTCQR VSQEEVKKWA 60 ESLENLIHHE CGLAAFKAFL KSEYSEENID FWISCEEYKK IKSPSKLSPK AKKIYNEFIS 120 VQATKEVNLD SCTREETSRN MLQPTITCFD EAQKKIFNLM ERDSYRRFLK SRFYLDLTNP 180 SSCGAEKQKG AKSSADCTSL VSQCA 206 |
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Keyword | KW-0181--Complete proteome |
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Interpro | |||||||||
PROSITE | PS50132--RGS |
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Pfam | PF00615--RGS |
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Gene Ontology | GO:0005737--C:cytoplasm |