dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000379
Uniprot Accession O08843; LST1_MOUSE; O08844; Q9Z1H3; Q9Z1R0;
Genbank Protein ID
Genbank Nucleotide ID
Protein Name Leukocyte-specific transcript 1 protein
Protein Synonyms/Alias Protein B144;
Gene Name Lst1
Gene Synonyms/Alias B144;
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)		 Possible role in modulating immune responses. Has an inhibitory effect on lymphocyte proliferation. Induces morphological changes including production of filopodia and microspikes when overexpressed in a variety of cell types and may be involved in dendritic cell maturation.
Phosphorylation Sites
 dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
62VSGQEPHYASLQQLPPhosphoSitePlus22135298
64GQEPHYASLQQLPVSdbPTM 3.0;Phospho.ELM 9.0;PhosphoPep 2.0;PhosphoSitePlus19144319; 16381945; 23193290; 19060867; 22135298
Sequence
(Fasta)		MSDDNGSGNN CTTNHFLLYG SLGLGGLLLL LVIILFICLC GFSQRVKRLE RNAQVSGQEP 60
HYASLQQLPV SSSDITDMKE DLSTDYACIA RSTPT 96
Keyword

KW-0025--Alternative splicing
KW-0133--Cell shape
KW-0181--Complete proteome
KW-0391--Immunity
KW-0472--Membrane
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
Interpro

IPR007775--Leukocyte-sp_tscrpt_1_LST1
PROSITE
Pfam

PF05083--LST1
Gene Ontology

GO:0005737--C:cytoplasm
GO:0016021--C:integral component of membrane
GO:0000902--P:cell morphogenesis
GO:0016358--P:dendrite development
GO:0006955--P:immune response
GO:0050672--P:negative regulation of lymphocyte proliferation
GO:0008360--P:regulation of cell shape