dbPAF Protein Information
| Tag | Content | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| dbPAF ID | dbPAF-0000378 | ||||||||
| Uniprot Accession | O08842; GFRA2_MOUSE; Q3UUD8; Q920Y3; Q9Z2A2; Q9Z2A3; | ||||||||
| Genbank Protein ID | NP_001289023.1; NP_001289024.1; NP_032141.2; | ||||||||
| Genbank Nucleotide ID | NM_001302094.1; NM_001302095.1; NM_008115.3; | ||||||||
| Protein Name | GDNF family receptor alpha-2 | ||||||||
| Protein Synonyms/Alias | |||||||||
| Gene Name | Gfra2 | ||||||||
| Gene Synonyms/Alias | Gdnfrb;Trnr2; | ||||||||
| Organism | Mus musculus(Mouse) | ||||||||
| NCBI Taxa ID | 10090 | ||||||||
| Functional Description (View all) |
Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor. | ||||||||
| Phosphorylation Sites |
dbPAF PTMs: 1
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| Sequence (Fasta) | MILANAFCLF FFLDETLRSL ASPSSPQGSE LHGWRPQVDC VRANELCAAE SNCSSRYRTL 60 RQCLAGRDRN TMLANKECQA ALEVLQESPL YDCRCKRGMK KELQCLQIYW SIHLGLTEGE 120 EFYEASPYEP VTSRLSDIFR LASIFSGTGA DPVVSAKSNH CLDAAKACNL NDNCKKLRSS 180 YISICNREIS PTERCNRRKC HKALRQFFDR VPSEYTYRML FCSCQDQACA ERRRQTILPS 240 CSYEDKEKPN CLDLRSLCRT DHLCRSRLAD FHANCRASYR TITSCPADNY QACLGSYAGM 300 IGFDMTPNYV DSNPTGIVVS PWCNCRGSGN MEEECEKFLK DFTENPCLRN AIQAFGNGTD 360 VNMSPKGPTF SATQAPRVEK TPSLPDDLSD STSLGTSVIT TCTSIQEQGL KANNSKELSM 420 CFTELTTNIS PGSKKVIKLY SGSCRARLST ALTALPLLMV TLAQ 465 |
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| Keyword | KW-0025--Alternative splicing |
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| Interpro | IPR016017--GDNF/GAS1 |
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| PROSITE | |||||||||
| Pfam | PF02351--GDNF |
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| Gene Ontology | GO:0031225--C:anchored component of membrane |