Tag |
Content |
dbPAF ID |
dbPAF-0000354 |
Uniprot Accession |
O08769; O08769_RAT; |
Genbank Protein ID |
NP_113950.2; XP_006237601.1; |
Genbank Nucleotide ID |
NM_031762.3; XM_006237539.2; |
Protein Name |
Cyclin dependent kinase inhibitor |
Protein Synonyms/Alias |
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Gene Name |
Cdkn1b |
Gene Synonyms/Alias |
p27Kip1;rCG_29991; |
Organism |
Rattus norvegicus(Rat) |
NCBI Taxa ID |
10116 |
Functional Description (View all) |
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Phosphorylation Sites
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dbPAF PTMs: 4 |
Sequence (Fasta) | MSNVRVSNGS PSLERMDARQ TEHPKPSACR NLFGPVNHEE LTRDLEKHCR DMEEASQRKW 60 NFDFQNHKPL EGRYEWQEVE RGSLPEFYYR PPRPPKSACK VPAQESLDVS GSRQAVPSIG 120 SQANSEDRHL VDQMPDSSDS PAGLAEQCPG MRKRPAAEDS SSQNKRANRT EENVSDGSPN 180 AGTVEQTPKK PGLRRQT
198Fasta Sequence
>O08769|Cdkn1b|Rattus norvegicus(Rat) MSNVRVSNGSPSLERMDARQTEHPKPSACRNLFGPVNHEELTRDLEKHCRDMEEASQRKWNFDFQNHKPLEGRYEWQEVERGSLPEFYYRPPRPPKSACKVPAQESLDVSGSRQAVPSIGSQANSEDRHLVDQMPDSSDSPAGLAEQCPGMRKRPAAEDSSSQNKRANRTEENVSDGSPNAGTVEQTPKKPGLRRQT
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Keyword |
KW-0175--Coiled coil KW-0181--Complete proteome KW-0195--Cyclin KW-0418--Kinase KW-1267--Proteomics identification KW-1185--Reference proteome KW-0808--Transferase
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Interpro |
IPR003175--CDI IPR029843--CDKN1B
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PROSITE |
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Pfam |
PF02234--CDI
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Gene Ontology |
GO:0031464--C:Cul4A-RING E3 ubiquitin ligase complex GO:0005737--C:cytoplasm GO:0005829--C:cytosol GO:0005634--C:nucleus GO:0043234--C:protein complex GO:0051087--F:chaperone binding GO:0004861--F:cyclin-dependent protein serine/threonine kinase inhibitor activity GO:0008656--F:cysteine-type endopeptidase activator activity involved in apoptotic process GO:0030544--F:Hsp70 protein binding GO:0016301--F:kinase activity GO:0032403--F:protein complex binding GO:0048102--P:autophagic cell death GO:0008219--P:cell death GO:0071236--P:cellular response to antibiotic GO:0071285--P:cellular response to lithium ion GO:0071407--P:cellular response to organic cyclic compound GO:0000082--P:G1/S transition of mitotic cell cycle GO:0048839--P:inner ear development GO:0071850--P:mitotic cell cycle arrest GO:0043066--P:negative regulation of apoptotic process GO:0030308--P:negative regulation of cell growth GO:0008285--P:negative regulation of cell proliferation GO:0051271--P:negative regulation of cellular component movement GO:0045736--P:negative regulation of cyclin-dependent protein serine/threonine kinase activity GO:0060770--P:negative regulation of epithelial cell proliferation involved in prostate gland development GO:0045930--P:negative regulation of mitotic cell cycle GO:0045892--P:negative regulation of transcription, DNA-templated GO:0007219--P:Notch signaling pathway GO:0008284--P:positive regulation of cell proliferation GO:0045737--P:positive regulation of cyclin-dependent protein serine/threonine kinase activity GO:0031116--P:positive regulation of microtubule polymerization GO:0045732--P:positive regulation of protein catabolic process GO:0006813--P:potassium ion transport GO:0043200--P:response to amino acid GO:0046686--P:response to cadmium ion GO:0042493--P:response to drug GO:0032355--P:response to estradiol GO:0009749--P:response to glucose GO:0001666--P:response to hypoxia GO:0014070--P:response to organic cyclic compound GO:0043434--P:response to peptide hormone GO:0007605--P:sensory perception of sound
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