| Tag |
Content |
| dbPAF ID |
dbPAF-0000352 |
| Uniprot Accession |
O08762; NETR_MOUSE;
|
| Genbank Protein ID |
NP_032965.1;
|
| Genbank Nucleotide ID |
NM_008939.2;
|
| Protein Name |
Neurotrypsin |
| Protein Synonyms/Alias |
Brain-specific serine protease 3;BSSP-3;Motopsin;Serine protease 12; |
| Gene Name |
Prss12 |
| Gene Synonyms/Alias |
Bssp3; |
| Organism |
Mus musculus(Mouse) |
| NCBI Taxa ID |
10090 |
Functional Description
(View all) |
Plays a role in neuronal plasticity and the proteolytic action may subserve structural reorganizations associated with learning and memory operations.Functional Description
Plays a role in neuronal plasticity and the proteolytic action may subserve structural reorganizations associated with learning and memory operations. |
Phosphorylation Sites
|
dbPAF PTMs: 1 | Position | Peptides | Source | References ( PMIDs ) |
|---|
| 493 | DYLEKKASSSGNKEM | PhosphoSitePlus | 22135298 |
|
Sequence
(Fasta) | MALARCVLAV ILGALSVVAR ADPVSRSPLH RPHPSPPRSQ HAHYLPSSRR PPRTPRFPLP 60
LRIPAAQRPQ VLSTGHTPPT IPRRCGAGES WGNATNLGVP CLHWDEVPPF LERSPPASWA 120
ELRGQPHNFC RSPDGSGRPW CFYRNAQGKV DWGYCDCGQG PALPVIRLVG GNSGHEGRVE 180
LYHAGQWGTI CDDQWDNADA DVICRQLGLS GIAKAWHQAH FGEGSGPILL DEVRCTGNEL 240
SIEQCPKSSW GEHNCGHKED AGVSCVPLTD GVIRLAGGKS THEGRLEVYY KGQWGTVCDD 300
GWTEMNTYVA CRLLGFKYGK QSSVNHFDGS NRPIWLDDVS CSGKEVSFIQ CSRRQWGRHD 360
CSHREDVGLT CYPDSDGHRL SPGFPIRLVD GENKKEGRVE VFVNGQWGTI CDDGWTDKHA 420
AVICRQLGYK GPARARTMAY FGEGKGPIHM DNVKCTGNEK ALADCVKQDI GRHNCRHSED 480
AGVICDYLEK KASSSGNKEM LSSGCGLRLL HRRQKRIIGG NNSLRGAWPW QASLRLRSAH 540
GDGRLLCGAT LLSSCWVLTA AHCFKRYGNN SRSYAVRVGD YHTLVPEEFE QEIGVQQIVI 600
HRNYRPDRSD YDIALVRLQG PGEQCARLST HVLPACLPLW RERPQKTASN CHITGWGDTG 660
RAYSRTLQQA AVPLLPKRFC KERYKGLFTG RMLCAGNLQE DNRVDSCQGD SGGPLMCEKP 720
DESWVVYGVT SWGYGCGVKD TPGVYTRVPA FVPWIKSVTS L
762Fasta Sequence
>O08762|Prss12|Mus musculus(Mouse)
MALARCVLAVILGALSVVARADPVSRSPLHRPHPSPPRSQHAHYLPSSRRPPRTPRFPLPLRIPAAQRPQVLSTGHTPPTIPRRCGAGESWGNATNLGVPCLHWDEVPPFLERSPPASWAELRGQPHNFCRSPDGSGRPWCFYRNAQGKVDWGYCDCGQGPALPVIRLVGGNSGHEGRVELYHAGQWGTICDDQWDNADADVICRQLGLSGIAKAWHQAHFGEGSGPILLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCVPLTDGVIRLAGGKSTHEGRLEVYYKGQWGTVCDDGWTEMNTYVACRLLGFKYGKQSSVNHFDGSNRPIWLDDVSCSGKEVSFIQCSRRQWGRHDCSHREDVGLTCYPDSDGHRLSPGFPIRLVDGENKKEGRVEVFVNGQWGTICDDGWTDKHAAVICRQLGYKGPARARTMAYFGEGKGPIHMDNVKCTGNEKALADCVKQDIGRHNCRHSEDAGVICDYLEKKASSSGNKEMLSSGCGLRLLHRRQKRIIGGNNSLRGAWPWQASLRLRSAHGDGRLLCGATLLSSCWVLTAAHCFKRYGNNSRSYAVRVGDYHTLVPEEFEQEIGVQQIVIHRNYRPDRSDYDIALVRLQGPGEQCARLSTHVLPACLPLWRERPQKTASNCHITGWGDTGRAYSRTLQQAAVPLLPKRFCKERYKGLFTGRMLCAGNLQEDNRVDSCQGDSGGPLMCEKPDESWVVYGVTSWGYGCGVKDTPGVYTRVPAFVPWIKSVTSL
|
| Keyword |
KW-0181--Complete proteome
KW-1015--Disulfide bond
KW-0325--Glycoprotein
KW-0378--Hydrolase
KW-0420--Kringle
KW-0645--Protease
KW-1185--Reference proteome
KW-0677--Repeat
KW-0964--Secreted
KW-0720--Serine protease
KW-0732--Signal
|
| Interpro |
IPR000001--Kringle
IPR013806--Kringle-like
IPR018056--Kringle_CS
IPR018114--Peptidase_S1_AS
IPR009003--Peptidase_S1_PA
IPR001314--Peptidase_S1A
IPR001190--SRCR
IPR017448--SRCR-like_dom
IPR001254--Trypsin_dom
|
| PROSITE |
PS00021--KRINGLE_1
PS50070--KRINGLE_2
PS00420--SRCR_1
PS50287--SRCR_2
PS50240--TRYPSIN_DOM
PS00134--TRYPSIN_HIS
PS00135--TRYPSIN_SER
|
| Pfam |
PF00051--Kringle
PF00530--SRCR
PF00089--Trypsin
|
| Gene Ontology |
GO:0030424--C:axon
GO:0031410--C:cytoplasmic vesicle
GO:0030425--C:dendrite
GO:0005886--C:plasma membrane
GO:0045202--C:synapse
GO:0043083--C:synaptic cleft
GO:0043195--C:terminal bouton
GO:0008233--F:peptidase activity
GO:0005044--F:scavenger receptor activity
GO:0004252--F:serine-type endopeptidase activity
GO:0006887--P:exocytosis
GO:0006508--P:proteolysis
GO:0031638--P:zymogen activation
|
